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Add consolidated group project
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---
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title: "IEMSB - Imaging Empowered Multiscale Biophysics (2026-2029)"
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summary: IEMSB brings together advanced imaging, artificial intelligence, chemistry and quantitative biophysics to connect molecular mechanisms with cellular and tissue function.
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date: 2026-01-01
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end_date: 2029-12-31
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funding: €649,000
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funding_agency: "Gobierno Vasco - Ayudas para apoyar las actividades de grupos de investigación del sistema universitario vasco (2026-2029)"
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draft: false
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featured: true
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authors: ["Ignacio Arganda-Carreras", "Fadi Dornaika", "Nagore Barrena", "Unai Elordi", "Aitor González-Marfil"]
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image:
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filename: "euskal-jaurlaritza-logo.png"
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focal_point: "center"
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preview_only: true
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tags:
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- Multiscale Biophysics
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- Advanced Imaging
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- Artificial Intelligence
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- Bioimage Analysis
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- Fluorescence Microscopy
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- Cryo-Electron Microscopy
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---
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The **Imaging Empowered Multiscale Biophysics (IEMSB)** initiative has been officially funded under the **Ayudas para apoyar las actividades de grupos de investigación del sistema universitario vasco (2026-2029)** programme. The final resolution was communicated on **24 August 2026**.
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Led by **Dr. Virginia Martinez-Martinez** and **Dr. Ignacio Arganda-Carreras**, IEMSB unites researchers from the University of the Basque Country (UPV/EHU) and the Spanish National Research Council (CSIC) at the Instituto Biofisika. The initiative connects molecular, cellular and tissue scales through advanced imaging, computation and quantitative biophysics.
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<figure>
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<img src="iemsb-figure.png" alt="IEMSB bridges cellular structure, tissue biophysics, AI-based imaging and chemistry through Basque imaging platforms" width="460">
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<figcaption><b>Fig. 1:</b> IEMSB: Bridging scales through Imaging, Al, Chemistry and Biophysics. An initiative to foster scientific excellence, interdisciplinary training, and international impact.</figcaption>
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</figure>
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---
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### 🔬 Scientific Goals
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IEMSB is organised around four complementary research lines:
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- **Structural Biology and Cellular Architecture**: resolving macromolecular structures and dynamics in native cellular environments using cryo-EM, cryo-ET and correlative fluorescence microscopy.
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- **Tissue Biophysics**: understanding how cell-ECM interactions, forces and adhesion dynamics shape neural and epithelial tissues during development, repair and ageing.
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- **AI-Based Tools for Imaging**: developing interpretable, scalable and data-efficient methods for denoising, segmentation, classification, particle picking and subtomogram analysis.
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- **Chemistry-Driven Tools for Imaging**: designing fluorophores, fluorogenic probes and biosensors for quantitative and super-resolution imaging of molecular events in living systems.
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The programme works in close coordination with the Basque imaging platforms **BRALM** (advanced light microscopy), **BREM** (electron microscopy) and **BRAIIAN** (AI and image analysis). Together, these platforms provide an integrated framework for imaging-driven multiscale biophysics.
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---
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### 🌐 Basque Imaging Platforms
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- **BRALM**: advanced light and super-resolution microscopy.
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- **BREM**: cryo-electron microscopy, cryo-electron tomography and correlative imaging.
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- **BRAIIAN**: artificial intelligence, computer vision and image analysis.
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---
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### 👥 Project Team
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#### Principal Investigators
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- Dr. **Virginia Martinez-Martinez** (Permanent Doctor Researcher, UPV/EHU)
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- Dr. **Ignacio Arganda-Carreras** (Ikerbasque Research Associate Professor, UPV/EHU; DIPC; Biofisika Institute)
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#### CVPD Team
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- Dr. **Fadi Dornaika** (Ikerbasque Research Professor, UPV/EHU)
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- Dr. **Nagore Barrena** (Assistant Professor, UPV/EHU)
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- Dr. **Unai Elordi** (Assistant Professor, UPV/EHU)
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- **Aitor González-Marfil** (PhD student, UPV/EHU; DIPC)
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The wider IEMSB group comprises 22 members, including 21 doctors and one predoctoral researcher, with expertise spanning physical chemistry, biochemistry, molecular biology, computer science and artificial intelligence.
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---
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### 🕒 Timeline
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- **Start date**: 1 January 2026
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- **End date**: 31 December 2029
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- **Duration**: 48 months
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---
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### 💰 Funding
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- **Call**: [Ayudas para apoyar las actividades de grupos de investigación del sistema universitario vasco (2026-2029)](https://www.euskadi.eus/ayuda_subvencion/2026/ikertalde/web01-tramite/es/)
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- **Funding body**: Gobierno Vasco / Euskal Jaurlaritza
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- **Resolution**: 24 August 2026
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- **Granted total**: **649,000 €**
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<img src="euskal-jaurlaritza-logo.png" alt="Euskal Jaurlaritza - Gobierno Vasco" width="660">
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---
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### 📄 Project Documentation
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- [Official programme and call information](https://www.euskadi.eus/ayuda_subvencion/2026/ikertalde/web01-tramite/es/)
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- Final funding resolution communicated on **24 August 2026**
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---
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### 📬 Contacts
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For project enquiries, please contact:
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- [Dr. Ignacio Arganda-Carreras](mailto:ignacio.arganda@ehu.eus)
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- [Dr. Virginia Martinez-Martinez](mailto:virgina.martinez@ehu.eus)

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