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| 1 | +--- |
| 2 | +title: "TOSBI – Towards Scalable and Generalized Solutions in Biomedical Images (2025-2028)" |
| 3 | +summary: TOSBI develops scalable and generalizable deep learning methods for biomedical image analysis, focusing on limited annotation, computational efficiency and robust transferability. |
| 4 | +date: 2025-09-01 |
| 5 | +authors: ["Ignacio Arganda-Carreras", "Fadi Dornaika", "Nagore Barrena", "Unai Elordi", "Aitor González-Marfil", "Daniel Franco-Barranco"] |
| 6 | +draft: false |
| 7 | +featured: true |
| 8 | +image: |
| 9 | + focal_point: "center" |
| 10 | + preview_only: false |
| 11 | +tags: |
| 12 | + - Biomimage Analysis |
| 13 | + - Deep Learning |
| 14 | + - Scalability |
| 15 | + - Domain Generalization |
| 16 | + - Foundation Models |
| 17 | +--- |
| 18 | + |
| 19 | +The **TOSBI** project — *"Towards Scalable and Generalized Solutions in Biomedical Images"* — aims to develop deep learning methodologies that scale to large bioimage datasets and generalize across imaging modalities and laboratories, with a particular emphasis on annotation-efficient approaches and adapting foundation models to bioimage tasks. |
| 20 | + |
| 21 | +Led by the **Computer Vision and Pattern Discovery (CVPD)** group at the **University of the Basque Country (UPV/EHU)**, TOSBI addresses key bottlenecks in modern biomedical image analysis: scarcity of high-quality annotations, computational cost of state-of-the-art models, and limited cross-domain generalization. |
| 22 | + |
| 23 | +### 🔬 Scientific Goals |
| 24 | + |
| 25 | +- Design and evaluate **annotation-efficient learning strategies** (self-supervised, semi-supervised, few-/zero-shot) tailored to biomedical images. |
| 26 | +- Improve **scalability** of model training and inference for large microscopy and histopathology datasets. |
| 27 | +- Develop **domain adaptation and domain generalization** techniques to transfer models between imaging modalities, labs, or experimental conditions. |
| 28 | +- Adapt and validate **foundation models** for downstream bioimage tasks (segmentation, detection, classification), including practical tooling for the community. |
| 29 | +- Deliver open and reproducible software components and evaluation pipelines compatible with community platforms (e.g., BiaPy). |
| 30 | + |
| 31 | +### 👥 Project Team |
| 32 | + |
| 33 | +- **Principal Investigators**: |
| 34 | + - Dr. **Fadi Dornaika** (Ikerbasque Research Professor, UPV/EHU) |
| 35 | + - Dr. **Ignacio Arganda-Carreras** (Ikerbasque Research Associate Professor, UPV/EHU, DIPC, Biofisika Institute) |
| 36 | + |
| 37 | +- **Research Team**: |
| 38 | + - Dr. **Urtzi Ayesta** (Ikerbasque Research Professor, UPV/EHU) |
| 39 | + - Dr. **Nagore Barrena** (Assistant Professor, UPV/EHU) |
| 40 | + - Dr. **Unai Elordi** (Assistant Professor, UPV/EHU) |
| 41 | + |
| 42 | +- **Work Team / Collaborators**: |
| 43 | + - **Aitor González-Marfil** (PhD student, CVPD) |
| 44 | + - **Estibaliz Gómez de Mariscal** (Postdoctoral researcher, Portugal) |
| 45 | + - **Daniel Franco-Barranco** (Postdoctoral researcher / collaborator, UK) |
| 46 | + - **Dr. Jinan Charafeddine** (De Vinci Higher Education, France) |
| 47 | + - **Dr. Fares Bougourzi** (University of Salento, Italy) |
| 48 | + - **Dr. Donglai Wei** (Boston College, USA) |
| 49 | + - **Software engineer (SE)** (to be hired — WP8) |
| 50 | + - **PhD candidate (FPI)** (to be recruited — linked FPI contract) |
| 51 | + |
| 52 | +For the complete list of roles and the contribution of each member, see the project application PDF linked below. |
| 53 | + |
| 54 | +### 🕒 Timeline |
| 55 | + |
| 56 | +- **Start**: September, 1 2025 |
| 57 | +- **Duration**: August, 31 2028 |
| 58 | + |
| 59 | +### 💰 Funding |
| 60 | + |
| 61 | +- Funded by the **Spanish Ministry of Science, Innovation and Universities (MCIU)** under the **Generación de Conocimiento 2024 (Proyectos de Investigación No Orientada)** program, MICIU/AEI /10.13039/501100011033/, and by FEDER, EU. |
| 62 | +- **Total funding**: 143,250.00€ (including indirect costs) |
| 63 | +- Reference code: **PID2024-157485NB-I00** |
| 64 | + |
| 65 | + |
| 66 | +<img src="/assets/media/MICIU_Cofinanciado_AEI_logo.jpg" alt="Spanish State Agency for Research (AEI) Logo" width="500"> |
| 67 | + |
| 68 | +--- |
| 69 | + |
| 70 | +### 📄 Project documentation |
| 71 | + |
| 72 | +- Related [PhD announcement](/post/2025-09-30-phd-offer-tosbi/). |
| 73 | + |
| 74 | +--- |
| 75 | + |
| 76 | +### 📬 Contacts |
| 77 | + |
| 78 | +- For project-specific enquiries: [Dr. Fadi Dornaika](mailto:fadi.dornaika@ehu.eus) and [Dr. Ignacio Arganda-Carreras](mailto:ignacio.arganda@ehu.eus) |
| 79 | + |
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