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<h2 class="section-title fade-up">Research</h2>
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<p class="section-intro fade-up">
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We apply mostly computational approaches, particularly those involving the analysis of
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high-throughput genomic and transcriptomic data, to fundamental questions in biomedical
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research, namely in the context of cancer, neurobiology, and ageing. By integrating
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transcriptomic data with molecular and clinical information, we aim to identify novel
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regulatory mechanisms and molecular targets across three interconnected research themes.
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We apply computational and evolutionary approaches, involving
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the analysis of high-throughput genomic and transcriptomic data,
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to fundamental questions in biomedical research on human
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diseases, namely cancer and ageing-related pathologies. We also
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build open tools for assisting non-computational scientists in
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their analyses of transcriptomic and other types of biomedical data.
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</p>
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<span class="rfilter-dot cancer"></span>RNA in cancer
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</button>
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<button class="research-filter-btn" data-filter="neuro">
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<span class="rfilter-dot neuro"></span>Neuro-biology
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<span class="rfilter-dot neuro"></span>Neurobiology
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</button>
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<button class="research-filter-btn" data-filter="evolutionary">
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<span class="rfilter-dot evolutionary"></span>Evolutionary biology
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<button class="research-filter-btn" data-filter="bioinformatics">
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<span class="rfilter-dot bioinformatics"></span>Bioinformatics tools
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<button class="research-filter-btn" data-filter="biostatistics">
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<span class="rfilter-dot biostatistics"></span>Biostatistics
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<button class="research-filter-btn" data-filter="evolutionary">
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<span class="rfilter-dot evolutionary"></span>Evolutionary biology
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<button class="research-filter-btn" data-filter="external">
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<span class="rfilter-dot external"></span>External collaboration
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<span class="research-keyword">transcriptomics</span>
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</div>
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<div class="research-card-people">
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<strong>Members:</strong> Rita Martins-Silva, Maria Guerra (alumna), Mariana Ascensão-Ferreira (alumna), Nuno Barbosa-Morais (PI)<br>
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<strong>Members:</strong> Rita Martins-Silva, Alessandro Minguzzi, Maria Guerra (alumna), Mariana Ascensão-Ferreira (alumna), Nuno Barbosa-Morais (PI)<br>
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<strong>Collaborators:</strong> <a href="https://lms.mrc.ac.uk/research/senescence/" target="_blank" rel="noopener">Jesús Gil</a>, <a href="https://www.researchgate.net/profile/Maria_Vivo" target="_blank" rel="noopener">Maria Vivo</a>
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</div>
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<div class="research-card-toggle">
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<span class="research-keyword">immunodeficiency</span>
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</div>
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<div class="research-card-people">
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<strong>Members:</strong> Francisca Xara-Brasil, Alexandre Kaizeler, Nuno Barbosa-Morais (co-PI)<br>
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<strong>Members:</strong> Francisca Xara-Brasil, Alexandre Kaizeler<br>
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<strong>Collaborators:</strong> Carolina Pinto, <a href="https://www.vmartinslab.com/contact" target="_blank" rel="noopener">Vera Martins</a> (PI)
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</div>
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<div class="research-card-toggle">
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<span class="research-keyword">transcriptomics</span>
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</div>
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<div class="research-card-people">
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<strong>Members:</strong> Alexandre Kaizeler, Nuno Barbosa-Morais (co-PI)<br>
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<strong>Members:</strong> Alexandre Kaizeler<br>
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<strong>Collaborators:</strong> Gabriela Lima da Silva, <a href="https://www.medicina.ulisboa.pt/en/bio/anaseb" target="_blank" rel="noopener">Ana Sebastião</a> (PI)
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</div>
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<div class="research-card-toggle">

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