Welcome to the official documentation for PROTACXtend — an open-source AI platform for target-to-lead PROTAC discovery, generative linker assembly, ternary complex modeling, and degradation prediction.
Developed at Ahuja Lab (Department of Computational Biology, IIIT Delhi) by Saveena Solanki and team.
| Section | Description | Link |
|---|---|---|
| 🚀 Getting Started | Installation, environment setup, dependencies, fast-track quickstart | GETTING_STARTED.md |
| 🏗️ Architecture & Feynman Stack | 23-node agentic workflow graph, supervisor engine, physics + ML stack | ARCHITECTURE.md |
| ⚡ Workflows & Slash Commands | CLI slash commands (/design, /predict, /dock, /admet, /audit, /replicate) |
WORKFLOWS.md |
| 🔌 API & CLI Reference | Complete Python API (protacxtend), REST endpoints, and CLI interface |
API_REFERENCE.md |
| 🐙 GitHub & Collaboration | Repository details (the-ahuja-lab/PROTACXtend), Saveena Solanki collaborator setup |
GITHUB_AND_COLLABORATION.md |
Explore the interactive web landing page and local science workbench in the website/ directory:
- Open
website/index.htmldirectly in your browser. - Or launch via python local web server:
python -m http.server 8000 --directory website
- Or launch the Streamlit science workbench UI:
protacxtend serve
- GitHub Repository:
https://github.com/the-ahuja-lab/PROTACXtend - Primary Maintainer: Saveena Solanki (@SaveenaSolanki)
- Organization: Ahuja Lab (@the-ahuja-lab)