ddi_enzyme_database.csv

drug_A,drug_B,enzymes,mechanism,severity,in_trial,trial_AEs,in_trueDDI
Methotrexate,Trimethoprim,ABCB1 (P-gp),"transporter induction, transporter inhibition",Major,Yes,185,Yes
Cyclophosphamide,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Major,Yes,130,Yes
Carboplatin,Sorafenib,ABCC2 (MRP2),transporter inhibition,Major,Yes,63,Yes
Celecoxib,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Major,Yes,27,Yes
Thalidomide,Vincristine,CYP3A5,CYP induction,Major,Yes,16,No
Tamoxifen,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Major,Yes,10,Yes
Cyclophosphamide,Thiotepa,"CYP2B6, CYP3A4","CYP induction, CYP inhibition",Major,Yes,1,Yes
Bupropion,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Leflunomide,Rofecoxib,CYP1A2,CYP inhibition,Major,No,0,No
Erythromycin,Leflunomide,CYP1A2,CYP inhibition,Major,No,0,No
Fluconazole,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Major,No,0,No
Aspirin,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Bupropion,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Major,No,0,Yes
Celecoxib,Ketorolac,PTGS2,CYP inhibition,Major,No,0,Yes
Citalopram,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Major,No,0,No
Ketoprofen,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Celecoxib,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Etodolac,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Fentanyl,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Major,No,0,No
Citalopram,Sorafenib,CYP3A4,CYP inhibition,Major,No,0,No
Leflunomide,Pioglitazone,CYP2C9,CYP inhibition,Major,No,0,No
Arthrotec,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Carbamazepine,Bortezomib,CYP1A2,"CYP induction, CYP inhibition",Major,No,0,Yes
Vincristine,Voriconazole,CYP3A4,CYP inhibition,Major,No,0,Yes
Ibuprofen,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Fenofibrate,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Itrizole,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Fluoxetine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Ondansetron,Arsenic Trioxide,CYP3A4,CYP inhibition,Major,No,0,Yes
Paroxetine,Tamoxifen,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Leflunomide,Lovastatin,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Fluconazole,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Phenytoin,Leflunomide,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Indomethacin,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Acetaminophen,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Busulfan,Metronidazole,CYP3A4,CYP inhibition,Major,No,0,Yes
Bicalutamide,Citalopram,CYP2D6,CYP inhibition,Major,No,0,No
Lansoprazole,Erlotinib,"ABCG2 (BCRP), CYP1A2, CYP2C8","CYP induction, CYP inhibition, transporter inhibition",Major,No,0,Yes
Ifosfamide,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Major,No,0,No
Medroxyprogesterone,Bosentan,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Major,No,0,Yes
Leflunomide,Oxaprozin,CYP2C9,CYP inhibition,Major,No,0,No
Arsenic Trioxide,Palonosetron,CYP3A4,CYP inhibition,Major,No,0,No
Leflunomide,Thalidomide,CYP2C9,CYP inhibition,Major,No,0,No
Atorvastatin EP Impurity B,Leflunomide,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Carbamazepine,Leflunomide,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Major,No,0,No
Ifosfamide,Thiotepa,"CYP2B6, CYP3A4","CYP induction, CYP inhibition",Major,No,0,No
Hydroxychloroquine,Tamoxifen,CYP2D6,CYP inhibition,Major,No,0,No
Azathioprine,6-Mercaptopurine,HPRT1,CYP inhibition,Major,No,0,Yes
Leflunomide,Bosentan,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Valproic Acid,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Anzemet,Mitoxantrone,CYP3A4,CYP inhibition,Major,No,0,No
Cimetidine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Fentanyl,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Major,No,0,No
Leflunomide,Valdecoxib,CYP2C9,CYP inhibition,Major,No,0,No
Thalidomide,Capecitabine,CYP2C9,CYP inhibition,Major,No,0,No
Leflunomide,Simvastatin,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Isoniazid,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
Ciprofloxacin,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Major,No,0,Yes
Prochlorperazine,Arsenic Trioxide,CYP3A4,CYP inhibition,Major,No,0,No
Clotrimazole,Leflunomide,CYP2C9,CYP inhibition,Major,No,0,No
5-Fluorouracil,Thalidomide,CYP2C9,CYP inhibition,Major,No,0,No
Carbamazepine,Imatinib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Citalopram,Arsenic Trioxide,CYP3A4,CYP inhibition,Major,No,0,Yes
Lansoprazole,Dasatinib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Major,No,0,Yes
Anzemet,Arsenic Trioxide,CYP3A4,CYP inhibition,Major,No,0,No
Anzemet,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Major,No,0,No
Cyclophosphamide,Leflunomide,CYP2C9,"CYP induction, CYP inhibition",Major,No,0,No
Ritonavir,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Arthrotec,Dasatinib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Major,No,0,No
Ritonavir,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Major,No,0,Yes
Itrizole,Dasatinib,"ABCB1 (P-gp), CYP1A1, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Major,No,0,Yes
Pantoprazole,Dasatinib,"ABCB1 (P-gp), CYP1A2","CYP induction, transporter inhibition",Major,No,0,Yes
Pantoprazole,Erlotinib,"ABCG2 (BCRP), CYP1A2","CYP induction, transporter inhibition",Major,No,0,Yes
Indomethacin,Methotrexate,ABCC2 (MRP2),transporter inhibition,Major,No,0,Yes
Lansoprazole,Methotrexate,ABCB1 (P-gp),transporter inhibition,Major,No,0,Yes
Ketoprofen,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,Yes
Methotrexate,Pantoprazole,ABCB1 (P-gp),transporter inhibition,Major,No,0,Yes
Diflunisal,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,No
Ofloxacin,Arsenic Trioxide,ABCC2 (MRP2),"transporter induction, transporter inhibition",Major,No,0,Yes
Simvastatin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Major,No,0,Yes
Ibuprofen,Dasatinib,ABCB1 (P-gp),transporter inhibition,Major,No,0,No
Arthrotec,Methotrexate,ABCC1,transporter inhibition,Major,No,0,Yes
Etodolac,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,Yes
Ibuprofen,Methotrexate,ABCC1,transporter inhibition,Major,No,0,Yes
Aspirin,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,Yes
Lovastatin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Major,No,0,No
Flurbiprofen,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,Yes
Aspirin,Dasatinib,ABCB1 (P-gp),transporter inhibition,Major,No,0,No
Atorvastatin EP Impurity B,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Major,No,0,Yes
Furosemide,Arsenic Trioxide,ABCC2 (MRP2),"transporter induction, transporter inhibition",Major,No,0,Yes
Amoxicillin,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Major,No,0,Yes
Clopidogrel,Dasatinib,ABCB1 (P-gp),transporter inhibition,Major,No,0,No
Tamoxifen,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Major,No,0,No
5-Fluorouracil,Capecitabine,CYP2C9,CYP inhibition,Moderate,Yes,465,Yes
Methotrexate,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,Yes,208,Yes
Cyclophosphamide,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,Yes,188,Yes
Methotrexate,Imatinib,ABCB1 (P-gp),transporter inhibition,Moderate,Yes,188,Yes
Imatinib,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,Yes,185,Yes
Imatinib,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,Yes,173,Yes
Cyclophosphamide,5-Fluorouracil,CYP2C9,"CYP induction, CYP inhibition",Moderate,Yes,123,Yes
Thalidomide,Bortezomib,CYP1A2,CYP inhibition,Moderate,Yes,104,No
Vincristine,Bortezomib,CYP3A4,CYP inhibition,Moderate,Yes,99,Yes
Hydroxyurea,Imatinib,CYP2D6,CYP inhibition,Moderate,Yes,85,Yes
Celecoxib,Arthrotec,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Moderate,Yes,82,Yes
Cyclophosphamide,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,Yes,75,Yes
Imatinib,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Moderate,Yes,70,Yes
Ifosfamide,Vinblastine,CYP3A4,"CYP induction, CYP inhibition",Moderate,Yes,65,Yes
Cyclophosphamide,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,Yes,62,Yes
Doxorubicin,Methotrexate,ABCC1,transporter inhibition,Moderate,Yes,50,Yes
Bicalutamide,CID 152945,CYP3A4,CYP inhibition,Moderate,Yes,49,No
Erlotinib,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Moderate,Yes,42,No
Cyclophosphamide,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,Yes,40,Yes
Anastrozole,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,Yes,33,Yes
Busulfan,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,Yes,28,Yes
Methotrexate,Mitoxantrone,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,Yes,27,Yes
Cyclophosphamide,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,Yes,26,Yes
Vinblastine,Carboplatin,ABCC2 (MRP2),"transporter induction, transporter inhibition",Moderate,Yes,26,Yes
Acetaminophen,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,Yes,20,No
Methotrexate,Vinblastine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,Yes,9,Yes
Methotrexate,Carboplatin,ABCC2 (MRP2),transporter inhibition,Moderate,Yes,4,Yes
Celecoxib,Indomethacin,"ABCC4 (MRP4), PTGS2","CYP inhibition, transporter inhibition",Moderate,Yes,1,Yes
Celecoxib,Tramadol,CYP3A4,CYP inhibition,Moderate,Yes,1,No
Fluoxetine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Metoprolol,Imatinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Fluconazole,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Loratadine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Dapsone,Bortezomib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Itrizole,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Risperidone,CYP3A4,CYP inhibition,Moderate,No,0,No
Carvedilol,Celecoxib,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Promethazine,Tamoxifen,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Ibuprofen,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Citalopram,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Amlodipine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Donepezil,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Ciprofloxacin,Thalidomide,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Glibenclamide,CYP3A4,CYP inhibition,Moderate,No,0,No
Lovastatin,Bortezomib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Propranolol,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Ondansetron,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Carvedilol,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Ifosfamide,Imatinib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Leflunomide,Metronidazole,CYP2C9,CYP inhibition,Moderate,No,0,No
Celecoxib,Venlafaxine,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Metoprolol,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Timolol,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Ofloxacin,Thalidomide,CYP1A2,CYP inhibition,Moderate,No,0,No
Modafinil,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Metronidazole,Bortezomib,CYP3A4,CYP inhibition,Moderate,No,0,No
Glimepiride,Imatinib,CYP2C9,CYP inhibition,Moderate,No,0,No
Temazepam,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,No
Celecoxib,Ketoprofen,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Amlodipine,Thalidomide,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Amitriptyline,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Ciprofloxacin,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Citalopram,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Thalidomide,Timolol,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Voriconazole,Bortezomib,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Metronidazole,Thalidomide,CYP2C9,CYP inhibition,Moderate,No,0,No
Valproic Acid,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Clopidogrel,Bortezomib,CYP1A2,CYP inhibition,Moderate,No,0,No
Celecoxib,Prochlorperazine,CYP2D6,CYP inhibition,Moderate,No,0,No
Celecoxib,Haloperidol,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Metronidazole,CYP3A4,CYP inhibition,Moderate,No,0,No
5-Fluorouracil,Metronidazole,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Gemfibrozil,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Carbamazepine,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Paroxetine,Thalidomide,CYP2C9,CYP inhibition,Moderate,No,0,No
Phenytoin,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Thalidomide,Venlafaxine,CYP2C19,CYP inhibition,Moderate,No,0,No
Lovastatin,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Prochlorperazine,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Loperamide,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Imatinib,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Salbutamol,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Quetiapine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Promethazine,CYP2C9,CYP inhibition,Moderate,No,0,No
Clonazepam,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Fluoxetine,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Cyclophosphamide,Glibenclamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Imatinib,Zolpidem,CYP3A4,CYP inhibition,Moderate,No,0,No
Thalidomide,Simvastatin,CYP2C9,"CYP induction, CYP inhibition",Moderate,No,0,No
Metronidazole,Vincristine,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Ciprofloxacin,CYP3A4,CYP inhibition,Moderate,No,0,No
Glimepiride,Bortezomib,CYP2C9,CYP inhibition,Moderate,No,0,No
Glipizide,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Clotrimazole,Bortezomib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Nortriptyline,CYP2D6,CYP inhibition,Moderate,No,0,No
Pioglitazone,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Ifosfamide,Zolpidem,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Acetaminophen,Busulfan,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Glibenclamide,Leflunomide,"ABCG2 (BCRP), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Mitoxantrone,Thiotepa,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Clopidogrel,CYP2C9,CYP inhibition,Moderate,No,0,No
Glibenclamide,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Risperidone,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Irbesartan,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Busulfan,Itrizole,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Itrizole,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Clonazepam,Thalidomide,CYP2E1,CYP inhibition,Moderate,No,0,Yes
Fenofibrate,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Fluoxetine,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Cyclophosphamide,Metronidazole,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Losartan,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Diflunisal,PTGS2,CYP inhibition,Moderate,No,0,Yes
Bicalutamide,Prochlorperazine,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Mirtazapine,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Busulfan,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Labetalol,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Fluconazole,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Thalidomide,Zolpidem,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Celecoxib,Ticlopidine,CYP3A4,CYP inhibition,Moderate,No,0,No
Carbamazepine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Acetaminophen,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Metoprolol,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Quetiapine,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Tamoxifen,Venlafaxine,"ABCB1 (P-gp), ABCG2 (BCRP), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Erythromycin,Gefitinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Chloroquine,CYP2D6,CYP inhibition,Moderate,No,0,No
Ondansetron,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Doxepin,CYP2D6,CYP inhibition,Moderate,No,0,No
Fluconazole,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Timolol,Gefitinib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Fluvoxamine,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Meclizine,Thalidomide,CYP1A2,CYP inhibition,Moderate,No,0,Yes
Verapamil,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Imipramine,CYP2D6,CYP inhibition,Moderate,No,0,No
Doxazosin,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,No
Celecoxib,Flurbiprofen,"ABCC4 (MRP4), PTGS2","CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Amitriptyline,Celecoxib,CYP2D6,CYP inhibition,Moderate,No,0,No
Phenytoin,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Trazodone,CYP2D6,CYP inhibition,Moderate,No,0,No
Celecoxib,Nabumetone,PTGS2,CYP inhibition,Moderate,No,0,Yes
Itrizole,Medroxyprogesterone,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Nifedipine,Thalidomide,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Verapamil,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Imatinib,Capecitabine,CYP2C9,CYP inhibition,Moderate,No,0,No
Celecoxib,Ondansetron,CYP2D6,CYP inhibition,Moderate,No,0,No
Cyclobenzaprine,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Carbamazepine,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Prochlorperazine,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Leflunomide,Torasemide,CYP2C9,CYP inhibition,Moderate,No,0,No
Celecoxib,Isoniazid,CYP3A4,CYP inhibition,Moderate,No,0,No
Itrizole,Bortezomib,"CYP1A1, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Carbamazepine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,5-Aminosalicylic Acid,PTGS2,CYP inhibition,Moderate,No,0,No
Diazepam,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Glipizide,Leflunomide,CYP2C9,CYP inhibition,Moderate,No,0,No
Capecitabine,Sorafenib,CYP2C9,CYP inhibition,Moderate,No,0,No
Citalopram,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Atorvastatin EP Impurity B,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Mirtazapine,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Nefazodone,Medroxyprogesterone,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Etodolac,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Darifenacin,CYP2D6,CYP inhibition,Moderate,No,0,No
Celecoxib,Paroxetine,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Quetiapine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Loperamide,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Diazepam,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Nortriptyline,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Atorvastatin EP Impurity B,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Fluconazole,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Ondansetron,Dasatinib,CYP1A2,CYP inhibition,Moderate,No,0,No
Simvastatin,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Ondansetron,Thalidomide,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Promethazine,Imatinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Oxaprozin,PTGS2,CYP inhibition,Moderate,No,0,No
Nifedipine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Bumetanide,Celecoxib,PTGS2,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Atorvastatin EP Impurity B,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Tamoxifen,Tramadol,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Prilosec,Gefitinib,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Loratadine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Glimepiride,Leflunomide,CYP2C9,CYP inhibition,Moderate,No,0,No
Promethazine,Thalidomide,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Erythromycin,Medroxyprogesterone,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Leflunomide,Losartan,CYP1A2,CYP inhibition,Moderate,No,0,No
Celecoxib,Valproic Acid,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Celecoxib,Mefenamic Acid,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Cyclophosphamide,Hydroxyurea,CYP2D6,CYP inhibition,Moderate,No,0,No
Ofloxacin,Tamoxifen,"ABCC2 (MRP2), CYP1A2","CYP inhibition, transporter inhibition",Moderate,No,0,No
Busulfan,Mitoxantrone,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Trimipramine,CYP2D6,CYP inhibition,Moderate,No,0,No
Ciprofloxacin,Dasatinib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Moderate,No,0,No
Clotrimazole,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Celecoxib,CYP2D6,CYP inhibition,Moderate,No,0,Yes
Thalidomide,Arsenic Trioxide,CYP1A1,CYP inhibition,Moderate,No,0,Yes
Lansoprazole,Imatinib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Aripiprazole,CYP2D6,"CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Cimetidine,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Prochlorperazine,Sorafenib,CYP3A4,CYP inhibition,Moderate,No,0,No
Ciprofloxacin,Gefitinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Venlafaxine,Sorafenib,"ABCB1 (P-gp), ABCG2 (BCRP), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Pantoprazole,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Glipizide,Bortezomib,CYP3A4,CYP inhibition,Moderate,No,0,No
Ondansetron,Sorafenib,CYP1A2,CYP inhibition,Moderate,No,0,No
Clotrimazole,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Ofloxacin,Dasatinib,CYP1A2,CYP inhibition,Moderate,No,0,No
Aspirin,Celecoxib,PTGS2,CYP inhibition,Moderate,No,0,Yes
Thalidomide,Voriconazole,"CYP2C9, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Fluconazole,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Atorvastatin EP Impurity B,Bexarotene,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Bicalutamide,Ketoconazole,CYP3A4,CYP inhibition,Moderate,No,0,No
Ibuprofen,Imatinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Fenofibrate,CYP2C9,CYP inhibition,Moderate,No,0,No
Ciprofloxacin,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Zafirlukast,CYP3A4,CYP inhibition,Moderate,No,0,No
Lansoprazole,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Bupropion,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Glibenclamide,Bortezomib,CYP3A4,CYP inhibition,Moderate,No,0,No
Atorvastatin EP Impurity B,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Imipramine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Propranolol,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Bicalutamide,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Lovastatin,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Hydroxyzine,Sorafenib,CYP2D6,CYP inhibition,Moderate,No,0,No
Thalidomide,Oxcarbazepine,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Ifosfamide,Mitoxantrone,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Rac-Efavirenz,Vincristine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Celecoxib,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Alprazolam,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Ifosfamide,Prochlorperazine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Paroxetine,Imatinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Mitoxantrone,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Medroxyprogesterone,Atazanavir,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Felodipine,Thalidomide,"CYP2C9, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Imipramine,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,No
Donepezil,Sorafenib,CYP3A4,CYP inhibition,Moderate,No,0,No
Simvastatin,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Fluconazole,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Atorvastatin EP Impurity B,Bicalutamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Bicalutamide,Tolterodine,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Amphetamine,CYP2D6,CYP inhibition,Moderate,No,0,No
Verapamil,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,Yes
Ropinirole,Thalidomide,CYP1A2,CYP inhibition,Moderate,No,0,Yes
Ketoconazole,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Phenytoin,5-Fluorouracil,CYP2C9,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Nefazodone,Thalidomide,CYP3A5,"CYP induction, CYP inhibition",Moderate,No,0,No
Respules,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Amitriptyline,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Clomipramine,CYP2D6,CYP inhibition,Moderate,No,0,No
Loratadine,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,No
Tramadol,Sorafenib,CYP3A4,CYP inhibition,Moderate,No,0,No
Fluconazole,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Nifedipine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Cyclophosphamide,Fenofibrate,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Triazolam,CYP2C9,CYP inhibition,Moderate,No,0,No
Carbamazepine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Fexofenadine,Sorafenib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Moderate,No,0,No
Fluoxetine,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Moderate,No,0,No
Risperidone,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Nifedipine,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Vincristine,Simvastatin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Celecoxib,Ritonavir,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Imatinib,Timolol,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Moderate,No,0,No
Celecoxib,Rac-Efavirenz,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Phenytoin,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Salbutamol,Dasatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Propranolol,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Simvastatin,Bexarotene,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Torasemide,CYP2C19,CYP inhibition,Moderate,No,0,No
Atorvastatin EP Impurity B,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Pioglitazone,Imatinib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Cyclophosphamide,Glipizide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Simvastatin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Fentanyl,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Salbutamol,Bicalutamide,CYP3A4,CYP inhibition,Moderate,No,0,No
Dapsone,Vincristine,CYP3A4,CYP inhibition,Moderate,No,0,No
Promethazine,Sorafenib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Moderate,No,0,No
Mitoxantrone,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Imatinib,Bosentan,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Temozolomide,Vinblastine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Busulfan,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Miconazole,CYP3A4,CYP inhibition,Moderate,No,0,No
Ifosfamide,Oxazepam,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Salbutamol,Flutamide,CYP3A4,CYP inhibition,Moderate,No,0,No
Salmeterol,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Losartan,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Hydroxyzine,Tamoxifen,CYP2D6,CYP inhibition,Moderate,No,0,No
Clonazepam,Imatinib,CYP3A4,CYP inhibition,Moderate,No,0,No
Fluconazole,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Lovastatin,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Bicalutamide,Venlafaxine,CYP3A4,CYP inhibition,Moderate,No,0,No
Erythromycin,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Fluconazole,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Valproic Acid,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Mirtazapine,Imatinib,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Dapsone,Imatinib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Tamoxifen,Aripiprazole,CYP2D6,"CYP induction, CYP inhibition",Moderate,No,0,No
Felodipine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Thalidomide,Sorafenib,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Norfloxacin,CYP3A4,CYP inhibition,Moderate,No,0,No
Celecoxib,Sulfadiazine,CYP2C9,CYP inhibition,Moderate,No,0,No
Oxcarbazepine,Sorafenib,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Dapsone,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Moderate,No,0,No
Celecoxib,Perphenazine,CYP2D6,CYP inhibition,Moderate,No,0,No
Mirtazapine,Sorafenib,"CYP1A2, CYP2D6","CYP induction, CYP inhibition",Moderate,No,0,No
Tamoxifen,Trimipramine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Clomipramine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Lovastatin,Imatinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Carbamazepine,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Verapamil,Erlotinib,"ABCB1 (P-gp), ABCG2 (BCRP), CYP2C8","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Arthrotec,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Salbutamol,Arsenic Trioxide,CYP3A4,CYP inhibition,Moderate,No,0,No
Isoniazid,Thalidomide,"CYP2C19, CYP2E1","CYP induction, CYP inhibition",Moderate,No,0,No
Alfuzosin,Bicalutamide,CYP3A4,CYP inhibition,Moderate,No,0,No
Carisoprodol,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,No
Fluconazole,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Vincristine,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Metronidazole,Capecitabine,CYP2C9,CYP inhibition,Moderate,No,0,Yes
Ifosfamide,Venlafaxine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Mitoxantrone,Nifedipine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Ritonavir,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Venlafaxine,Dasatinib,"ABCB1 (P-gp), ABCG2 (BCRP), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Doxepin,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Clomipramine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Imatinib,Oxcarbazepine,"CYP2C19, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Voriconazole,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Erythromycin,Bortezomib,CYP1A2,CYP inhibition,Moderate,No,0,Yes
Cyclophosphamide,Bosentan,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Venlafaxine,"ABCB1 (P-gp), ABCG2 (BCRP), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Ifosfamide,Paroxetine,CYP2C9,"CYP induction, CYP inhibition",Moderate,No,0,No
Ciprofloxacin,Erlotinib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Moderate,No,0,No
Doxepin,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Cyclophosphamide,Indapamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Imatinib,Tolterodine,CYP3A4,CYP inhibition,Moderate,No,0,No
Hydroxychloroquine,Imatinib,CYP2D6,CYP inhibition,Moderate,No,0,No
Carbamazepine,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Ifosfamide,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Modafinil,Sorafenib,CYP1A2,"CYP induction, CYP inhibition",Moderate,No,0,No
Alprazolam,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Fluconazole,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,Yes
Rac-Efavirenz,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Nortriptyline,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Ifosfamide,Promethazine,CYP2C9,"CYP induction, CYP inhibition",Moderate,No,0,No
Oxcarbazepine,Gefitinib,"CYP2C19, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,No
Phenytoin,Erlotinib,"CYP2C8, CYP3A4","CYP induction, CYP inhibition",Moderate,No,0,Yes
Phenytoin,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Moderate,No,0,Yes
Celecoxib,Voriconazole,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Salbutamol,Sorafenib,CYP3A4,CYP inhibition,Moderate,No,0,No
Norfloxacin,Sorafenib,CYP1A2,CYP inhibition,Moderate,No,0,No
Tamoxifen,Torasemide,CYP2C19,CYP inhibition,Moderate,No,0,No
Nevirapine,Vinblastine,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Tamoxifen,Trazodone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Moderate,No,0,No
Norfloxacin,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Moderate,No,0,No
Voriconazole,Erlotinib,CYP3A4,CYP inhibition,Moderate,No,0,Yes
Loperamide,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Moderate,No,0,No
Phenytoin,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Moderate,No,0,Yes
Meperidine,Thalidomide,CYP2C19,CYP inhibition,Moderate,No,0,Yes
Fentanyl,Thalidomide,CYP3A5,CYP induction,Moderate,No,0,Yes
Alprazolam,Thalidomide,CYP3A5,CYP induction,Moderate,No,0,Yes
Risperidone,Thalidomide,CYP3A5,CYP induction,Moderate,No,0,Yes
Celecoxib,Bosentan,CYP3A4,CYP induction,Moderate,No,0,No
Clonidine,Thalidomide,CYP3A5,CYP induction,Moderate,No,0,Yes
Phenytoin,Busulfan,CYP3A4,CYP induction,Moderate,No,0,Yes
Medroxyprogesterone,Oxcarbazepine,CYP3A4,CYP induction,Moderate,No,0,Yes
(3H)granisetron,Thalidomide,CYP3A5,CYP induction,Moderate,No,0,No
Cyclophosphamide,Glimepiride,CYP2C9,CYP induction,Moderate,No,0,No
Carbamazepine,Exemestane,CYP3A4,CYP induction,Moderate,No,0,No
Letrozole,Oxcarbazepine,CYP3A4,CYP induction,Moderate,No,0,No
Methotrexate,Norfloxacin,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,No,0,No
Valproic Acid,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,No,0,No
Doxorubicin,Ofloxacin,ABCC1,transporter inhibition,Moderate,No,0,No
Lovastatin,Methotrexate,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,No
5-Fluorouracil,Mitoxantrone,ABCG2 (BCRP),transporter inhibition,Moderate,No,0,No
Methotrexate,Ofloxacin,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,No
Methotrexate,Simvastatin,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Erythromycin,Methotrexate,"ABCB1 (P-gp), ABCC1","transporter induction, transporter inhibition",Moderate,No,0,No
Doxorubicin,Mitoxantrone,ABCC1,transporter inhibition,Moderate,No,0,No
Methotrexate,Tamoxifen,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,No
Furosemide,Carboplatin,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,Yes
Itrizole,Methotrexate,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,No,0,No
Hydrochlorothiazide,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,No,0,No
Carbamazepine,Methotrexate,"ABCB1 (P-gp), ABCC2 (MRP2)","transporter induction, transporter inhibition",Moderate,No,0,No
Theophylline,Methotrexate,SLC22A7,transporter inhibition,Moderate,No,0,No
Carboplatin,Bortezomib,SLC31A1,transporter inhibition,Moderate,No,0,No
Clotrimazole,Methotrexate,"ABCB1 (P-gp), ABCC2 (MRP2)","transporter induction, transporter inhibition",Moderate,No,0,No
Fluconazole,Methotrexate,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Doxorubicin,Verapamil,ABCC1,transporter inhibition,Moderate,No,0,Yes
Pantoprazole,Carboplatin,ABCG2 (BCRP),transporter inhibition,Moderate,No,0,No
Celecoxib,Dipyridamole,ABCC4 (MRP4),transporter inhibition,Moderate,No,0,No
Phenytoin,Methotrexate,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,Yes
Doxorubicin,Ritonavir,ABCC1,"transporter induction, transporter inhibition",Moderate,No,0,Yes
Methotrexate,Rofecoxib,ABCC4 (MRP4),transporter inhibition,Moderate,No,0,Yes
Glibenclamide,Megestrol,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Vincristine,Carboplatin,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,No
Methotrexate,Pioglitazone,SLCO1B1,transporter inhibition,Moderate,No,0,No
Lansoprazole,Carboplatin,ABCG2 (BCRP),transporter inhibition,Moderate,No,0,No
Enalapril,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Moderate,No,0,No
Ciprofloxacin,Methotrexate,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,Yes
Carbamazepine,Megestrol,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,Yes
Phenytoin,Megestrol,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,Yes
Gemfibrozil,Methotrexate,SLCO1B1,transporter inhibition,Moderate,No,0,No
Paroxetine,Dasatinib,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Imatinib,Carboplatin,ABCG2 (BCRP),transporter inhibition,Moderate,No,0,No
Methotrexate,Zoledronic Acid,ABCC1,transporter inhibition,Moderate,No,0,No
Celecoxib,Methotrexate,ABCC4 (MRP4),transporter inhibition,Moderate,No,0,Yes
Mitoxantrone,Carboplatin,ABCG2 (BCRP),transporter inhibition,Moderate,No,0,No
Methotrexate,Ritonavir,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,Yes
Loperamide,Dasatinib,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
5-Fluorouracil,Methotrexate,ABCC3,transporter inhibition,Moderate,No,0,No
Ketoconazole,Methotrexate,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Tamoxifen,Mitomycin C,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,No
Cyclophosphamide,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Atorvastatin EP Impurity B,Methotrexate,ABCC2 (MRP2),transporter inhibition,Moderate,No,0,No
Doxorubicin,Erythromycin,ABCC1,transporter inhibition,Moderate,No,0,No
Mitoxantrone,Mitomycin C,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,No
Methotrexate,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Moderate,No,0,No
Mitomycin C,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Moderate,No,0,Yes
Methotrexate,Nefazodone,ABCB1 (P-gp),transporter induction,Moderate,No,0,No
Methotrexate,6-Mercaptopurine,SLCO1B3? (OATP),transporter inhibition,Minor,Yes,199,Yes
Doxorubicin,Vincristine,ABCC1,transporter inhibition,Minor,Yes,196,Yes
Doxorubicin,Vinblastine,ABCC1,"transporter induction, transporter inhibition",Minor,Yes,69,Yes
Vincristine,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Minor,Yes,65,Yes
Cyclophosphamide,Indomethacin,"ABCB1 (P-gp), CYP2C19, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Minor,Yes,5,Yes
Prilosec,Bortezomib,CYP3A4,CYP inhibition,Minor,No,0,No
Celecoxib,Tolterodine,CYP2D6,CYP inhibition,Minor,No,0,No
Modafinil,Erlotinib,CYP1A2,"CYP induction, CYP inhibition",Minor,No,0,No
Citalopram,Imatinib,CYP3A4,CYP inhibition,Minor,No,0,No
Valproic Acid,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Tamoxifen,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Minor,No,0,No
Atorvastatin EP Impurity B,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Minor,No,0,No
Pantoprazole,Bortezomib,CYP1A2,"CYP induction, CYP inhibition",Minor,No,0,No
Clopidogrel,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Minor,No,0,No
Ciprofloxacin,5-Fluorouracil,CYP1A2,CYP inhibition,Minor,No,0,No
Ciprofloxacin,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Minor,No,0,No
Pioglitazone,Medroxyprogesterone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Minor,No,0,No
Citalopram,Bortezomib,CYP3A4,CYP inhibition,Minor,No,0,No
Cyclophosphamide,Ondansetron,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Minor,No,0,No
Busulfan,Ciprofloxacin,CYP3A4,CYP inhibition,Minor,No,0,No
Ciprofloxacin,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Minor,No,0,No
Ciprofloxacin,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Celecoxib,Donepezil,CYP2D6,CYP inhibition,Minor,No,0,No
Ciprofloxacin,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Minor,No,0,No
Metronidazole,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Verapamil,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Minor,No,0,No
5-Fluorouracil,Ofloxacin,CYP1A2,CYP inhibition,Minor,No,0,No
Donepezil,Gefitinib,CYP2C9,CYP inhibition,Minor,No,0,No
Celecoxib,Ranolazine,CYP3A4,CYP inhibition,Minor,No,0,No
Propranolol,Bortezomib,CYP1A2,CYP inhibition,Minor,No,0,No
Modafinil,Bortezomib,CYP1A2,"CYP induction, CYP inhibition",Minor,No,0,No
Cyclophosphamide,Norfloxacin,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Cimetidine,5-Fluorouracil,"CYP2C9, SLC22A7","CYP inhibition, transporter inhibition",Minor,No,0,No
Carmustine,Ofloxacin,CYP1A2,CYP inhibition,Minor,No,0,No
Diazepam,Bortezomib,CYP1A2,CYP inhibition,Minor,No,0,No
Modafinil,Imatinib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Minor,No,0,No
Donepezil,Imatinib,CYP3A4,CYP inhibition,Minor,No,0,No
Ciprofloxacin,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Norfloxacin,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Minor,No,0,No
Tolterodine,Gefitinib,CYP2C9,CYP inhibition,Minor,No,0,No
Ciprofloxacin,Thiotepa,CYP3A4,CYP inhibition,Minor,No,0,No
Carmustine,Ciprofloxacin,CYP1A2,CYP inhibition,Minor,No,0,No
Mitoxantrone,Norfloxacin,CYP3A4,CYP inhibition,Minor,No,0,No
Methotrexate,Levetiracetam,ABCC2 (MRP2),transporter inhibition,Minor,No,0,No
Ofloxacin,Carboplatin,ABCC2 (MRP2),transporter inhibition,Minor,No,0,No
Ofloxacin,Vincristine,ABCC2 (MRP2),transporter inhibition,Minor,No,0,No
Chloroquine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Minor,No,0,No
Mitoxantrone,Ofloxacin,ABCC1,transporter inhibition,Minor,No,0,No
5-Fluorouracil,Vincristine,ABCC3,transporter inhibition,Minor,No,0,No
Ciprofloxacin,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Minor,No,0,No
Tamoxifen,Exemestane,"CYP19A1, CYP3A4","CYP induction, CYP inhibition",Unknown,Yes,430,Yes
Cyclophosphamide,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,Yes,293,Yes
Cyclophosphamide,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,Yes,216,Yes
Cyclophosphamide,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,195,Yes
Cyclophosphamide,Trimethoprim,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,Yes,185,Yes
Trimethoprim,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,Yes,185,Yes
Carboplatin,Erlotinib,ABCG2 (BCRP),transporter inhibition,Unknown,Yes,130,Yes
Cyclophosphamide,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,Yes,119,No
Gefitinib,Erlotinib,"ABCG2 (BCRP), CYP2D6","CYP inhibition, transporter inhibition",Unknown,Yes,102,No
Anastrozole,Fulvestrant,CYP3A4,CYP inhibition,Unknown,Yes,91,Yes
Carboplatin,Gefitinib,ABCG2 (BCRP),transporter inhibition,Unknown,Yes,77,Yes
Ifosfamide,Vincristine,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,75,Yes
Letrozole,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,64,Yes
Cyclophosphamide,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,Yes,63,Yes
Celecoxib,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,62,Yes
Celecoxib,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,62,Yes
Celecoxib,Vincristine,CYP3A4,CYP inhibition,Unknown,Yes,62,Yes
Celecoxib,Vinblastine,CYP3A4,CYP inhibition,Unknown,Yes,62,Yes
Mitoxantrone,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,Yes,40,Yes
Anastrozole,Exemestane,CYP19A1,CYP inhibition,Unknown,Yes,35,Yes
Anastrozole,Capecitabine,CYP2C9,CYP inhibition,Unknown,Yes,26,Yes
Anastrozole,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,Yes,26,Yes
5-Fluorouracil,Tamoxifen,CYP2C9,CYP inhibition,Unknown,Yes,26,Yes
Anastrozole,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,26,Yes
Tamoxifen,Capecitabine,CYP2C9,CYP inhibition,Unknown,Yes,26,Yes
Temozolomide,Sorafenib,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,22,No
Celecoxib,5-Fluorouracil,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Unknown,Yes,13,No
Celecoxib,Capecitabine,CYP2C9,CYP inhibition,Unknown,Yes,13,No
Celecoxib,Temozolomide,CYP3A4,CYP induction,Unknown,Yes,13,No
Ifosfamide,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,10,Yes
Cyclophosphamide,Prilosec,"CYP2C19, CYP3A4","CYP induction, CYP inhibition",Unknown,Yes,5,Yes
Arsenic Trioxide,Bortezomib,CYP3A4,CYP inhibition,Unknown,Yes,4,No
5-Fluorouracil,Gefitinib,"ABCG2 (BCRP), CYP2C9","CYP inhibition, transporter inhibition",Unknown,Yes,3,Yes
Letrozole,Exemestane,CYP19A1,CYP inhibition,Unknown,Yes,3,Yes
Anastrozole,Letrozole,CYP19A1,CYP inhibition,Unknown,Yes,3,Yes
Temozolomide,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Unknown,Yes,3,No
Bicalutamide,Flutamide,CYP3A4,CYP inhibition,Unknown,Yes,3,Yes
Temozolomide,Erlotinib,CYP3A4,CYP induction,Unknown,Yes,1,Yes
Acetaminophen,Letrozole,"CYP2A6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Diazepam,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Enalapril,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Dapsone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Amlodipine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Propofol,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Zolpidem,CYP2D6,CYP inhibition,Unknown,No,0,No
Letrozole,Loratadine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Prilosec,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Tamoxifen,Zolpidem,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Temazepam,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Aspirin,Sorafenib,"ABCB1 (P-gp), CYP2C19, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Salbutamol,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Acetaminophen,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Leflunomide,Zopiclone,CYP2C9,CYP inhibition,Unknown,No,0,No
Paroxetine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Lansoprazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Hydroxychloroquine,CYP2D6,CYP inhibition,Unknown,No,0,No
Respules,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Nifedipine,"ABCC3, CYP1A2, CYP2C9","CYP induction, CYP inhibition, transporter induction",Unknown,No,0,No
Acetaminophen,Bortezomib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Metoprolol,CYP2D6,CYP inhibition,Unknown,No,0,No
Zolpidem,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Nisoldipine,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclobenzaprine,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Pantoprazole,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Simvastatin,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Aspirin,Tamoxifen,"ABCB1 (P-gp), CYP2C19, CYP2C9","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Prilosec,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Lansoprazole,Leflunomide,"ABCG2 (BCRP), CYP1A2, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Irbesartan,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Zolpidem,Sorafenib,CYP1A2,CYP inhibition,Unknown,No,0,No
3-(1-Methylpyrrolidin-2-yl)pyridine,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Enalapril,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Haloperidol,"ABCB1 (P-gp), CYP2D6, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Metronidazole,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Prochlorperazine,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Fluoxetine,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Fentanyl,CYP3A4,CYP inhibition,Unknown,No,0,No
Thalidomide,Tolterodine,CYP2C19,CYP inhibition,Unknown,No,0,No
Celecoxib,Doxazosin,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Isradipine,CYP3A4,CYP inhibition,Unknown,No,0,No
Clopidogrel,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Metoprolol,Tamoxifen,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Pioglitazone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Ondansetron,CYP1A2,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Propranolol,CYP1A2,CYP inhibition,Unknown,No,0,No
Lansoprazole,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Indapamide,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clopidogrel,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Letrozole,Methimazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Oxybutynin,CYP3A4,CYP inhibition,Unknown,No,0,No
Zolpidem,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Lidocaine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Ropinirole,CYP2D6,CYP inhibition,Unknown,No,0,No
Modafinil,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Pilocarpine,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Felodipine,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Losartan,CYP1A2,CYP inhibition,Unknown,No,0,No
Buspirone,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Ondansetron,CYP3A4,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Leflunomide,Trimethoprim,CYP2C9,CYP inhibition,Unknown,No,0,No
Carvedilol,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Mirtazapine,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Metoclopramide,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Ezetimibe,CYP3A4,CYP inhibition,Unknown,No,0,No
Theophylline,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Glibenclamide,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Prilosec,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Prochlorperazine,CYP2D6,CYP inhibition,Unknown,No,0,No
Acetaminophen,Lenalidomide,"ABCB1 (P-gp), PTGS2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Prochlorperazine,CYP3A4,CYP inhibition,Unknown,No,0,No
Acetaminophen,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Lidocaine,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Temozolomide,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Simvastatin,CYP2D6,CYP inhibition,Unknown,No,0,No
Loratadine,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Amlodipine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Anastrozole,Loratadine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Ezetimibe,CYP3A4,CYP inhibition,Unknown,No,0,No
Felodipine,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amoxicillin,Bortezomib,CYP2C19,CYP inhibition,Unknown,No,0,No
Fenofibrate,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Prilosec,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,Yes
Clopidogrel,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Leflunomide,Nifedipine,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Capecitabine,Desloratadine,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Pantoprazole,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Azelastine,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Cimetidine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Atovaquone,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Clopidogrel,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Tolterodine,CYP3A4,CYP inhibition,Unknown,No,0,No
Losartan,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Celecoxib,Nefazodone,CYP3A4,CYP inhibition,Unknown,No,0,No
Metoclopramide,Erlotinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Citalopram,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Ibuprofen,Tamoxifen,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Glibenclamide,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Lidocaine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Irbesartan,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Atorvastatin EP Impurity B,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Leflunomide,Venlafaxine,"ABCG2 (BCRP), CYP2C9","CYP inhibition, transporter induction",Unknown,No,0,No
Salbutamol,Anastrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Enalapril,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Leflunomide,Tolterodine,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Fluconazole,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Bicalutamide,Glibenclamide,CYP3A4,CYP inhibition,Unknown,No,0,No
Propranolol,Erlotinib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Imatinib,Desloratadine,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Nifedipine,Erlotinib,"ABCB1 (P-gp), CYP2C8, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Clopidogrel,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Pantoprazole,Imatinib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Anastrozole,Carvedilol,CYP1A2,CYP inhibition,Unknown,No,0,No
Meperidine,Vinblastine,CYP3A4,CYP inhibition,Unknown,No,0,No
Aspirin,Thalidomide,CYP2C19,"CYP induction, CYP inhibition",Unknown,No,0,No
Furosemide,Methotrexate,"ABCC2 (MRP2), PGD, SLCO1B1 (OATP1B1)","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclobenzaprine,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Pantoprazole,Thalidomide,"CYP1A2, CYP2C19","CYP induction, CYP inhibition",Unknown,No,0,No
Ofloxacin,Erlotinib,CYP1A2,CYP inhibition,Unknown,No,0,No
Amitriptyline,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Aspirin,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Bicalutamide,Metoprolol,CYP2D6,CYP inhibition,Unknown,No,0,No
Simvastatin,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Amlodipine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Busulfan,Fluconazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Aspirin,Imatinib,"ABCB1 (P-gp), CYP2C19, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Cyclobenzaprine,CYP2D6,CYP inhibition,Unknown,No,0,No
Lidocaine,Thalidomide,"CYP1A2, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Lansoprazole,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Lovastatin,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
5-Fluorouracil,Ibuprofen,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Pioglitazone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Alprazolam,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Phenytoin,Celecoxib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,Yes
Atorvastatin EP Impurity B,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Verapamil,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Losartan,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
Fenofibrate,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Pantoprazole,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Leflunomide,Temazepam,CYP2C9,CYP inhibition,Unknown,No,0,No
Metronidazole,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Ondansetron,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Loperamide,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Erythromycin,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Ropinirole,CYP1A2,CYP inhibition,Unknown,No,0,No
Bortezomib,Ezetimibe,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Rofecoxib,"ABCC4 (MRP4), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Fentanyl,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Clonazepam,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Losartan,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Diazepam,CYP1A2,CYP inhibition,Unknown,No,0,No
Acetaminophen,Celecoxib,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Isosorbide Mononitrate,CYP3A4,CYP inhibition,Unknown,No,0,No
Bupropion,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Prilosec,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Amlodipine,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Ondansetron,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Clopidogrel,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Ciprofloxacin,Leflunomide,CYP1A2,CYP inhibition,Unknown,No,0,No
Fluconazole,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Lidocaine,CYP3A4,CYP inhibition,Unknown,No,0,No
Citalopram,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Verapamil,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Alprazolam,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
(3H)granisetron,Bortezomib,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Aspirin,Lenalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Nifedipine,Bortezomib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Enalapril,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Voriconazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Pantoprazole,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Leflunomide,Propranolol,CYP1A2,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Voriconazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Metoclopramide,Bortezomib,CYP2D6,CYP inhibition,Unknown,No,0,No
Ibuprofen,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Amlodipine,Letrozole,CYP2A6,CYP inhibition,Unknown,No,0,No
Glimepiride,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Methylphenidate,Bortezomib,CYP2D6,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Pioglitazone,CYP2C9,CYP inhibition,Unknown,No,0,No
Oxazepam,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Irbesartan,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Leflunomide,Nisoldipine,CYP1A2,CYP inhibition,Unknown,No,0,No
Verapamil,5-Fluorouracil,"ABCC3, CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Paroxetine,CYP2C9,CYP inhibition,Unknown,No,0,No
Losartan,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Metronidazole,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Loratadine,Thalidomide,CYP2C19,"CYP induction, CYP inhibition",Unknown,No,0,No
Torasemide,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Losartan,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Tolterodine,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Quetiapine,CYP2D6,CYP inhibition,Unknown,No,0,No
Leflunomide,Triazolam,CYP2C9,CYP inhibition,Unknown,No,0,No
Amlodipine,Bicalutamide,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Tolterodine,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anzemet,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Alprazolam,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Pioglitazone,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Loperamide,CYP2D6,CYP inhibition,Unknown,No,0,No
Arthrotec,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Metoprolol,Sorafenib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Bicalutamide,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Methylphenidate,Tamoxifen,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Cerivastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Pantoprazole,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Leflunomide,Norfloxacin,CYP1A2,CYP inhibition,Unknown,No,0,No
Oxazepam,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Aspirin,Gefitinib,"ABCB1 (P-gp), CYP2C19, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Carmustine,Ondansetron,CYP1A2,CYP inhibition,Unknown,No,0,No
Memantine,Tamoxifen,CYP2B6,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Ondansetron,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Venlafaxine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Prilosec,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Bortezomib,Palonosetron,CYP1A2,CYP inhibition,Unknown,No,0,No
Celecoxib,Propofol,CYP3A4,CYP inhibition,Unknown,No,0,No
Ketoprofen,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Bupropion,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Pantoprazole,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Clopidogrel,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Sorafenib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Ofloxacin,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Raloxifene,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Ciprofloxacin,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Fexofenadine,CYP2D6,CYP inhibition,Unknown,No,0,No
Tolterodine,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Lansoprazole,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Ezetimibe,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Fexofenadine,Bortezomib,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Letrozole,"CYP2A6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Mirtazapine,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Amlodipine,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Valdecoxib,CYP2C9,CYP inhibition,Unknown,No,0,Yes
Ibuprofen,Ifosfamide,"CYP2C9, PTGS1","CYP induction, CYP inhibition",Unknown,No,0,No
Alprazolam,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clopidogrel,Flutamide,CYP1A2,CYP inhibition,Unknown,No,0,No
Diazepam,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Atovaquone,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Arthrotec,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Fluconazole,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Lansoprazole,CYP2D6,CYP inhibition,Unknown,No,0,No
Ibuprofen,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Ritonavir,CYP2D6,CYP inhibition,Unknown,No,0,Yes
Glibenclamide,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Propranolol,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Tolterodine,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Lovastatin,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Arsenic Trioxide,Simvastatin,"ABCB1 (P-gp), ABCC2 (MRP2), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Aspirin,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Salbutamol,Celecoxib,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Metoclopramide,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Lansoprazole,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Diazepam,CYP3A4,CYP inhibition,Unknown,No,0,Yes
Pantoprazole,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Clotrimazole,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Leflunomide,Desloratadine,CYP1A2,CYP inhibition,Unknown,No,0,No
Mirtazapine,Bortezomib,"CYP1A2, CYP2D6","CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Nevirapine,CYP2D6,CYP inhibition,Unknown,No,0,Yes
Enalapril,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Bupropion,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Tamoxifen,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Risperidone,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Glimepiride,CYP2C9,CYP inhibition,Unknown,No,0,No
Amlodipine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Phentermine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Simvastatin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Exemestane,Ezetimibe,CYP3A4,CYP inhibition,Unknown,No,0,No
Verapamil,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Nabumetone,Lenalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Imatinib,Telmisartan,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Loperamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Enalapril,CYP3A4,CYP inhibition,Unknown,No,0,No
Citalopram,Gefitinib,CYP2C19,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Oxazepam,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clonidine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Almotriptan,CYP2D6,CYP inhibition,Unknown,No,0,No
Propranolol,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Simvastatin,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Oxybutynin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Diazepam,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Leflunomide,Paroxetine,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclobenzaprine,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Citalopram,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Lovastatin,Sorafenib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Salbutamol,Erlotinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Diazepam,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Salbutamol,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Temazepam,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Torasemide,Sorafenib,CYP2C9,CYP inhibition,Unknown,No,0,No
Ibuprofen,Lenalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Metoclopramide,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Losartan,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Ibuprofen,CYP2C9,CYP inhibition,Unknown,No,0,No
Fluconazole,Erlotinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Raloxifene,CYP3A4,CYP inhibition,Unknown,No,0,No
Bupropion,Anastrozole,CYP1A2,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Bicalutamide,Isosorbide Mononitrate,CYP3A4,CYP inhibition,Unknown,No,0,No
Zolpidem,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Mirtazapine,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Propranolol,"ABCB1 (P-gp), CYP2D6, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Salbutamol,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Imatinib,Temazepam,CYP3A4,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Simvastatin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Haloperidol,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP2D6","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Itrizole,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Acetaminophen,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Lansoprazole,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Palonosetron,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Famciclovir,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Losartan,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Leflunomide,Loratadine,CYP2C9,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Letrozole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fentanyl,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Doxazosin,Sorafenib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
5-Fluorouracil,Glipizide,CYP2C9,CYP inhibition,Unknown,No,0,No
Temozolomide,Vincristine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Nifedipine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Famciclovir,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Diazepam,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Verapamil,Leflunomide,"ABCG2 (BCRP), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Itrizole,Thalidomide,"CYP2E1, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Arthrotec,CYP2C9,CYP inhibition,Unknown,No,0,No
Temazepam,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Losartan,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Alprazolam,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Promethazine,CYP2C9,CYP inhibition,Unknown,No,0,No
Anastrozole,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Citalopram,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Clonazepam,CYP3A4,CYP inhibition,Unknown,No,0,No
Fluconazole,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Lenalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Indomethacin,Lenalidomide,"ABCB1 (P-gp), PTGS2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Tamoxifen,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Rofecoxib,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Rofecoxib,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Bupropion,Sorafenib,CYP1A2,CYP inhibition,Unknown,No,0,No
Leflunomide,Pantoprazole,"ABCG2 (BCRP), CYP1A2, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Pioglitazone,Sorafenib,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Promethazine,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Prochlorperazine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Rivastigmine,CYP3A4,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Risperidone,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Clonidine,CYP1A2,CYP inhibition,Unknown,No,0,No
Amlodipine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Ondansetron,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Ondansetron,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Acetaminophen,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,(3H)granisetron,CYP2D6,"CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Losartan,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amlodipine,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
Carvedilol,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Torasemide,"CYP2C19, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Letrozole,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Ketoconazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Amlodipine,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Venlafaxine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Amlodipine,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amlodipine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Fentanyl,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Thalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Bisoprolol,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Fenofibrate,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Prilosec,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,Yes
Nifedipine,Sorafenib,"ABCB1 (P-gp), CYP1A2, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Thalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Anastrozole,Celecoxib,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Arthrotec,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Rofecoxib,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fluoxetine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Oxazepam,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Metoprolol,Bortezomib,CYP2C19,CYP inhibition,Unknown,No,0,No
Leflunomide,Promethazine,CYP2C9,CYP inhibition,Unknown,No,0,No
Anastrozole,Pioglitazone,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Felodipine,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Valproic Acid,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Clotrimazole,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Etodolac,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Atazanavir,CYP3A4,CYP inhibition,Unknown,No,0,Yes
5-Fluorouracil,Lansoprazole,"ABCG2 (BCRP), CYP1A2, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Bicalutamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Simvastatin,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Telmisartan,Sorafenib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Nifedipine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,Yes
Celecoxib,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Quetiapine,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Pantoprazole,"ABCG2 (BCRP), CYP1A2, CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Temazepam,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Clomipramine,Gefitinib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Raloxifene,CYP3A4,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Zolpidem,CYP3A4,CYP inhibition,Unknown,No,0,No
Acetaminophen,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Triazolam,CYP2C9,CYP inhibition,Unknown,No,0,No
Fluoxetine,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Diazepam,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Fenofibrate,Thalidomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Hydroxychloroquine,CYP2D6,CYP inhibition,Unknown,No,0,No
Glipizide,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Citalopram,Erlotinib,CYP2D6,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Oxybutynin,CYP2C8,CYP inhibition,Unknown,No,0,No
Loperamide,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Amlodipine,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Simvastatin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Fenofibrate,Bexarotene,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Carbamazepine,Carmustine,CYP1A2,"CYP induction, CYP inhibition",Unknown,No,0,No
Ofloxacin,Imatinib,CYP1A2,CYP inhibition,Unknown,No,0,No
Clonazepam,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Aspirin,Bicalutamide,"CYP2C19, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Lovastatin,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Valproic Acid,"CYP2A6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Glimepiride,Sorafenib,CYP2C9,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Ibuprofen,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Leflunomide,Mirtazapine,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Lovastatin,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Verapamil,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Acetaminophen,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Paroxetine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Verapamil,Celecoxib,"ABCC4 (MRP4), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Oxybutynin,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Citalopram,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Atazanavir,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Propranolol,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,CID 152945,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Doxazosin,Gefitinib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Mexiletine,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Methadone,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fexofenadine,Imatinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Bisoprolol,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,Yes
Verapamil,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Telmisartan,Bortezomib,CYP2C19,CYP inhibition,Unknown,No,0,No
Fexofenadine,Erlotinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Clopidogrel,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Respules,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Glipizide,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Promethazine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Clonidine,CYP2D6,CYP inhibition,Unknown,No,0,No
Metronidazole,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Glipizide,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Carvedilol,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Meperidine,CYP2D6,CYP inhibition,Unknown,No,0,No
Fluconazole,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Loratadine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Fentanyl,Erlotinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Fentanyl,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Salmeterol,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Temazepam,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Venlafaxine,"ABCG2 (BCRP), CYP2C9","CYP inhibition, transporter induction",Unknown,No,0,No
Salbutamol,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Indapamide,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Loperamide,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Acebutolol,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,Yes
Salbutamol,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Triazolam,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Metoprolol,Erlotinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Bicalutamide,Zolpidem,CYP3A4,CYP inhibition,Unknown,No,0,No
Carvedilol,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Letrozole,Venlafaxine,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Fexofenadine,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Fluoxetine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Ciprofloxacin,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Gemfibrozil,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Salbutamol,Gefitinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Ezetimibe,Erlotinib,"ABCG2 (BCRP), UGT1A1","CYP inhibition, transporter inhibition",Unknown,No,0,No
Glibenclamide,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amlodipine,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Zopiclone,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Isosorbide Mononitrate,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Triazolam,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Formoterol,CYP2D6,CYP inhibition,Unknown,No,0,No
Lidocaine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Irbesartan,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Felodipine,CYP3A4,CYP inhibition,Unknown,No,0,No
Alprazolam,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Diazepam,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Lansoprazole,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Simvastatin,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clonidine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Doxorubicin,Indomethacin,"ABCC1, UGT2B7","CYP inhibition, transporter inhibition",Unknown,No,0,No
Rofecoxib,Thalidomide,PTGS2,CYP inhibition,Unknown,No,0,No
Bupropion,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Carvedilol,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Venlafaxine,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Acetazolamide,Celecoxib,CYP3A4,CYP inhibition,Unknown,No,0,No
Nifedipine,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Busulfan,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Mirtazapine,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Irbesartan,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Methotrexate,Raloxifene,AOX1,CYP inhibition,Unknown,No,0,No
Carbamazepine,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Glipizide,CYP3A4,CYP inhibition,Unknown,No,0,No
Clonidine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Prochlorperazine,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Lovastatin,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
5-Fluorouracil,Mirtazapine,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Isoniazid,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Glimepiride,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Respules,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Fentanyl,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Ibuprofen,CYP2C9,CYP inhibition,Unknown,No,0,No
Arthrotec,5-Fluorouracil,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Rofecoxib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Methimazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Valproic Acid,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Venlafaxine,Erlotinib,"ABCG2 (BCRP), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Temazepam,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Bicalutamide,Clopidogrel,CYP2C9,CYP inhibition,Unknown,No,0,No
Diazepam,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Ibuprofen,"ABCB1 (P-gp), CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Clonidine,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Fluoxetine,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Zolpidem,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Ibuprofen,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Anzemet,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Thiotepa,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Ciprofloxacin,CYP1A2,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Loperamide,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Tolterodine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Raloxifene,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Clopidogrel,CYP2C9,CYP inhibition,Unknown,No,0,No
Capecitabine,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Clotrimazole,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Bupropion,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Clotrimazole,5-Fluorouracil,"ABCC3, CYP2C9","CYP inhibition, transporter induction",Unknown,No,0,No
Pioglitazone,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Celecoxib,Palonosetron,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Aspirin,CYP2C9,CYP inhibition,Unknown,No,0,No
Aspirin,Bortezomib,"CYP2C19, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Paroxetine,CYP2C9,CYP inhibition,Unknown,No,0,No
Bupropion,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Anzemet,CYP2D6,CYP inhibition,Unknown,No,0,No
3-(1-Methylpyrrolidin-2-yl)pyridine,5-Fluorouracil,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Atorvastatin EP Impurity B,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Fluconazole,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Chlordiazepoxide,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Methylphenidate,CYP2D6,CYP inhibition,Unknown,No,0,No
Clonidine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Amlodipine,Celecoxib,CYP2D6,CYP inhibition,Unknown,No,0,No
Alprazolam,Anastrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Zolpidem,CYP2C9,CYP inhibition,Unknown,No,0,No
Lansoprazole,Bortezomib,CYP1A2,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Zolpidem,CYP1A2,CYP inhibition,Unknown,No,0,No
Celecoxib,Clotrimazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Ezetimibe,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Leflunomide,Zolpidem,CYP2C9,CYP inhibition,Unknown,No,0,No
Isosorbide Mononitrate,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Metoprolol,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Loratadine,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Paroxetine,"ABCB1 (P-gp), CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Rofecoxib,"ABCC4 (MRP4), CYP3A4, PTGS2","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Fexofenadine,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Lansoprazole,Letrozole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Glipizide,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Tolterodine,CYP2D6,CYP inhibition,Unknown,No,0,No
Zolpidem,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Isosorbide Mononitrate,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Leflunomide,Ropinirole,CYP1A2,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Zolpidem,CYP2D6,CYP inhibition,Unknown,No,0,No
Fluconazole,Thiotepa,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Glibenclamide,"ABCC3, CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
(3H)granisetron,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Bicalutamide,Prilosec,CYP2C19,CYP inhibition,Unknown,No,0,No
Anastrozole,Arthrotec,CYP1A2,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Promethazine,"ABCB1 (P-gp), CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Fentanyl,Gefitinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Anastrozole,Fluoxetine,CYP1A2,CYP inhibition,Unknown,No,0,No
Irbesartan,Sorafenib,CYP1A2,CYP inhibition,Unknown,No,0,No
Naloxone,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Ketoconazole,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Irbesartan,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Irbesartan,CYP1A2,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Anzemet,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Loratadine,CYP2D6,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Prilosec,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Verapamil,CYP3A4,CYP inhibition,Unknown,No,0,No
Metoclopramide,Vinblastine,CYP2D6,CYP inhibition,Unknown,No,0,No
Metoclopramide,Imatinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Fenofibrate,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Letrozole,Losartan,CYP3A4,CYP inhibition,Unknown,No,0,No
Oxybutynin,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Fentanyl,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Arthrotec,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amitriptyline,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Metoclopramide,Tamoxifen,CYP2D6,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Oxybutynin,CYP3A4,CYP inhibition,Unknown,No,0,No
Salbutamol,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Letrozole,Raloxifene,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Letrozole,CYP2A6,CYP inhibition,Unknown,No,0,No
Felodipine,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Metronidazole,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Lansoprazole,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Valproic Acid,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Alprazolam,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Hydroxyzine,CYP2D6,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Metoclopramide,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Loratadine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Temazepam,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Pantoprazole,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Diazepam,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clotrimazole,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Lansoprazole,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Ifosfamide,Simvastatin,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Amitriptyline,Anastrozole,CYP1A2,CYP inhibition,Unknown,No,0,No
Tamoxifen,Desloratadine,"ABCB1 (P-gp), CYP1A2","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Fentanyl,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Hydroxyzine,CYP2D6,CYP inhibition,Unknown,No,0,No
Leflunomide,Nortriptyline,CYP2C9,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Irbesartan,CYP1A2,CYP inhibition,Unknown,No,0,No
Nifedipine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Carvedilol,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Valproic Acid,Letrozole,CYP2A6,"CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Atorvastatin EP Impurity B,Celecoxib,"ABCC4 (MRP4), CYP2D6, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Amoxicillin,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Glibenclamide,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Cyclobenzaprine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Ondansetron,Vinblastine,CYP3A4,CYP inhibition,Unknown,No,0,No
Busulfan,Diazepam,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Cyclobenzaprine,CYP1A2,CYP inhibition,Unknown,No,0,No
Celecoxib,Itrizole,CYP3A4,CYP inhibition,Unknown,No,0,No
Carvedilol,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Tamoxifen,Isosorbide Mononitrate,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Ondansetron,CYP1A2,CYP inhibition,Unknown,No,0,No
Anzemet,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Lansoprazole,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Clonazepam,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Carvedilol,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Nortriptyline,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Prochlorperazine,Vinblastine,CYP3A4,CYP inhibition,Unknown,No,0,No
Raloxifene,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Anastrozole,Venlafaxine,CYP3A4,CYP inhibition,Unknown,No,0,No
Acetaminophen,Erlotinib,"ABCB1 (P-gp), CYP2C8, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Zopiclone,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Salbutamol,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Lansoprazole,Thalidomide,"CYP1A2, CYP2C19","CYP induction, CYP inhibition",Unknown,No,0,No
Promethazine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Celecoxib,Trimethoprim,CYP2C9,CYP inhibition,Unknown,No,0,Yes
Lovastatin,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Ibuprofen,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Venlafaxine,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Quetiapine,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Verapamil,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Propranolol,CYP1A2,CYP inhibition,Unknown,No,0,No
Cyclobenzaprine,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Telmisartan,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Letrozole,Lovastatin,CYP3A4,CYP inhibition,Unknown,No,0,No
Prochlorperazine,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Zolpidem,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Lansoprazole,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Arthrotec,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Busulfan,Valproic Acid,CYP3A4,CYP inhibition,Unknown,No,0,No
Carmustine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Paroxetine,CYP2D6,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Venlafaxine,"ABCB1 (P-gp), ABCG2 (BCRP), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Desloratadine,CYP2C9,CYP inhibition,Unknown,No,0,No
Clopidogrel,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Temozolomide,Venlafaxine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Irbesartan,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Anastrozole,Losartan,CYP1A2,CYP inhibition,Unknown,No,0,No
Carvedilol,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Rac-Efavirenz,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,Yes
Leflunomide,Phentermine,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Atorvastatin EP Impurity B,Erlotinib,"ABCB1 (P-gp), CYP2C8, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Venlafaxine,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Clonazepam,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Tolterodine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Promethazine,Erlotinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Lidocaine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Hydroxyurea,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Loratadine,Bortezomib,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Irbesartan,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Fexofenadine,Gefitinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Irbesartan,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Ifosfamide,Prilosec,"CYP2C19, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Gefitinib,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
(3H)granisetron,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Irbesartan,Thalidomide,CYP1A2,CYP inhibition,Unknown,No,0,No
Etodolac,Tamoxifen,CYP2C9,CYP inhibition,Unknown,No,0,No
Bicalutamide,Doxazosin,CYP2C19,CYP inhibition,Unknown,No,0,No
Anastrozole,Prochlorperazine,CYP3A4,CYP inhibition,Unknown,No,0,No
Tamoxifen,Methimazole,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Arthrotec,Flutamide,CYP1A2,CYP inhibition,Unknown,No,0,No
Acetaminophen,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Thalidomide,Valdecoxib,PTGS2,CYP inhibition,Unknown,No,0,No
Paroxetine,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Itrizole,Thiotepa,CYP2B6,CYP inhibition,Unknown,No,0,No
Losartan,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Buspirone,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Doxazosin,Bortezomib,CYP2C19,CYP inhibition,Unknown,No,0,No
Fluoxetine,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Modafinil,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Triazolam,CYP2C9,CYP inhibition,Unknown,No,0,No
Respules,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Ketoprofen,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Tamoxifen,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Hydroxyurea,Hydroxyzine,CYP2D6,CYP inhibition,Unknown,No,0,No
Triazolam,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Letrozole,Tramadol,CYP3A4,CYP inhibition,Unknown,No,0,No
Glibenclamide,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Diazepam,Letrozole,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Loratadine,CYP2C9,CYP inhibition,Unknown,No,0,No
Atorvastatin EP Impurity B,5-Fluorouracil,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Thalidomide,Telmisartan,CYP2C19,CYP inhibition,Unknown,No,0,No
Leflunomide,Ticlopidine,CYP1A2,CYP inhibition,Unknown,No,0,No
Pantoprazole,Sorafenib,"ABCB1 (P-gp), CYP1A2","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Bicalutamide,Fentanyl,CYP3A4,CYP inhibition,Unknown,No,0,No
Thalidomide,Desloratadine,CYP1A2,CYP inhibition,Unknown,No,0,No
Verapamil,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Clonidine,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Capecitabine,Valdecoxib,CYP2C9,CYP inhibition,Unknown,No,0,No
Rofecoxib,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Midodrine,CYP2D6,CYP inhibition,Unknown,No,0,No
Pioglitazone,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Ketoprofen,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Naloxone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Acetaminophen,Anastrozole,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Glipizide,CYP3A4,CYP inhibition,Unknown,No,0,No
Felodipine,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Fluoxetine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Pioglitazone,Vincristine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Imatinib,Zopiclone,CYP3A4,CYP inhibition,Unknown,No,0,No
Metoprolol,Gefitinib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Salbutamol,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Gemfibrozil,"CYP1A2, CYP2C8","CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Glimepiride,CYP2C9,CYP inhibition,Unknown,No,0,No
Fluoxetine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Irbesartan,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Propofol,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Diazepam,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Amlodipine,Anastrozole,CYP1A2,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Quetiapine,CYP2D6,CYP inhibition,Unknown,No,0,No
Triazolam,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Oxybutynin,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Loratadine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Modafinil,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fluconazole,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Bicalutamide,Pantoprazole,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Mexiletine,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Clonazepam,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
(3H)granisetron,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Valproic Acid,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Lansoprazole,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Ondansetron,Erlotinib,CYP1A2,CYP inhibition,Unknown,No,0,No
Fexofenadine,Tamoxifen,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Ifosfamide,Pantoprazole,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Clopidogrel,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Simvastatin,Erlotinib,"ABCB1 (P-gp), CYP2C8, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Losartan,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Acetaminophen,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Metoclopramide,Sorafenib,CYP2D6,CYP inhibition,Unknown,No,0,No
Aspirin,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Carvedilol,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Tramadol,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Probenecid,"ABCB1 (P-gp), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Clonazepam,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Donepezil,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Ciprofloxacin,Imatinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Risperidone,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Temazepam,CYP2C9,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Temazepam,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Bicalutamide,Losartan,CYP3A4,CYP inhibition,Unknown,No,0,No
Bicalutamide,Carvedilol,CYP3A4,CYP inhibition,Unknown,No,0,No
Imatinib,Ezetimibe,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Amlodipine,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Oxazepam,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Prilosec,Vinblastine,CYP3A4,CYP inhibition,Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Bortezomib,CYP2D6,CYP inhibition,Unknown,No,0,No
Bupropion,Letrozole,CYP2A6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Ketoprofen,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Acebutolol,Cyclophosphamide,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Zopiclone,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Bisoprolol,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Pilocarpine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Leflunomide,Ofloxacin,CYP1A2,CYP inhibition,Unknown,No,0,No
Fenofibrate,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Fluconazole,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Vincristine,Gefitinib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Ciprofloxacin,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Rofecoxib,Arsenic Trioxide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Probenecid,"ABCC4 (MRP4), CYP2C9, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Clopidogrel,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Anastrozole,Atorvastatin EP Impurity B,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Clonidine,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Paroxetine,Sorafenib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Carvedilol,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Simvastatin,Fulvestrant,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,(3H)granisetron,CYP2D6,"CYP induction, CYP inhibition",Unknown,No,0,No
Letrozole,Ezetimibe,CYP3A4,CYP inhibition,Unknown,No,0,No
Bortezomib,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Ifosfamide,Lansoprazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Tramadol,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Hydralazine,CYP3A4,CYP inhibition,Unknown,No,0,No
Celecoxib,Dapsone,"CYP2C9, PTGS2","CYP induction, CYP inhibition",Unknown,No,0,No
Ifosfamide,Ondansetron,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
CID 152945,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Leflunomide,Primidone,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Famciclovir,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Temozolomide,Ezetimibe,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Dasatinib,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Anzemet,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Bicalutamide,Nifedipine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Venlafaxine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Tadalafil,CYP3A4,CYP inhibition,Unknown,No,0,No
Carmustine,Valproic Acid,CYP1A2,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Mirtazapine,CYP2D6,"CYP induction, CYP inhibition",Unknown,No,0,No
Leflunomide,Modafinil,CYP1A2,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Erythromycin,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Letrozole,Mirtazapine,CYP3A4,CYP inhibition,Unknown,No,0,No
Temozolomide,Arsenic Trioxide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Irbesartan,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Meperidine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Amlodipine,Flutamide,CYP1A2,CYP inhibition,Unknown,No,0,No
Torasemide,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Tramadol,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Salbutamol,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Bupropion,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Lidocaine,CYP1A2,CYP inhibition,Unknown,No,0,No
Celecoxib,Eletriptan,"CYP2D6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Mirtazapine,Erlotinib,"CYP2C8, CYP2D6","CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Lidocaine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Methylphenidate,Erlotinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Diazepam,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Loperamide,Gefitinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Hydroxyurea,Venlafaxine,CYP2D6,CYP inhibition,Unknown,No,0,No
Amlodipine,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Diazepam,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Anastrozole,Glibenclamide,CYP3A4,CYP inhibition,Unknown,No,0,No
Arthrotec,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Alprazolam,Bicalutamide,CYP3A4,CYP inhibition,Unknown,No,0,No
Trazodone,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Modafinil,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Oxybutynin,CYP2D6,CYP inhibition,Unknown,No,0,No
Rofecoxib,Gefitinib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Ciprofloxacin,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Verapamil,Arsenic Trioxide,"ABCB1 (P-gp), ABCC2 (MRP2), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,Yes
Alprazolam,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Carbamazepine,5-Fluorouracil,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Ibuprofen,Sorafenib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Trimethoprim,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Loratadine,Exemestane,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fentanyl,Flutamide,CYP3A4,CYP inhibition,Unknown,No,0,No
Thalidomide,Trimethoprim,CYP2C9,CYP inhibition,Unknown,No,0,No
Bicalutamide,Enalapril,CYP3A4,CYP inhibition,Unknown,No,0,No
Thalidomide,Gefitinib,"CYP2C9, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Imatinib,Isosorbide Mononitrate,CYP3A4,CYP inhibition,Unknown,No,0,No
3-(1-Methylpyrrolidin-2-yl)pyridine,Gefitinib,"CYP1A1, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Loratadine,Erlotinib,"ABCB1 (P-gp), CYP2C8, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Risperidone,Gefitinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Phenytoin,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,Yes
Indomethacin,Tamoxifen,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Mirtazapine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Erlotinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Lidocaine,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Oxazepam,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Bupropion,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Oxybutynin,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Temazepam,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Leflunomide,Propofol,CYP1A2,CYP inhibition,Unknown,No,0,No
Doxepin,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Ketoprofen,Tamoxifen,CYP2C9,CYP inhibition,Unknown,No,0,No
5-Fluorouracil,Haloperidol,CYP2C9,CYP inhibition,Unknown,No,0,No
Etodolac,Bortezomib,CYP2C9,CYP inhibition,Unknown,No,0,No
Clotrimazole,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Anastrozole,Fenofibrate,CYP2C9,CYP inhibition,Unknown,No,0,No
Tamoxifen,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Letrozole,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Mitoxantrone,Oxcarbazepine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Celecoxib,Thiothixene (USAN:USP),CYP2D6,CYP inhibition,Unknown,No,0,No
Felodipine,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Temozolomide,Tadalafil,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Desloratadine,"ABCB1 (P-gp), CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Indapamide,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Mirtazapine,Gefitinib,"CYP2C9, CYP2D6","CYP induction, CYP inhibition",Unknown,No,0,No
Irbesartan,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Losartan,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Rivastigmine,Erlotinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Pioglitazone,Erlotinib,"CYP2C8, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Itrizole,Arsenic Trioxide,"ABCB1 (P-gp), CYP1A1, CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclobenzaprine,Sorafenib,CYP1A2,CYP inhibition,Unknown,No,0,No
Donepezil,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,No
Vincristine,Arsenic Trioxide,"ABCB1 (P-gp), ABCC2 (MRP2), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
5-Fluorouracil,Fluoxetine,CYP1A2,CYP inhibition,Unknown,No,0,No
Clopidogrel,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Methylphenidate,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Losartan,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Arthrotec,Thalidomide,CYP2C19,CYP inhibition,Unknown,No,0,No
Lidocaine,Letrozole,CYP2A6,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Nifedipine,CYP2D6,CYP inhibition,Unknown,No,0,No
Paroxetine,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
Felodipine,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Pioglitazone,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Mitoxantrone,Bortezomib,CYP3A4,CYP inhibition,Unknown,No,0,No
Modafinil,Thalidomide,"CYP2C19, CYP3A5","CYP induction, CYP inhibition",Unknown,No,0,No
Diazepam,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Rac-Efavirenz,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,Yes
Felodipine,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Anastrozole,Zopiclone,CYP3A4,CYP inhibition,Unknown,No,0,No
Vincristine,Ezetimibe,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Verapamil,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Tamoxifen,Valdecoxib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Tamoxifen,Ezetimibe,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Letrozole,Oxybutynin,CYP3A4,CYP inhibition,Unknown,No,0,No
Arthrotec,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
Clonidine,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Tolterodine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Atovaquone,CYP2C9,CYP inhibition,Unknown,No,0,No
Celecoxib,Sorafenib,"ABCC4 (MRP4), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Letrozole,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Valproic Acid,Imatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Alprazolam,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Pilocarpine,Tamoxifen,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyzine,Gefitinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Letrozole,Risperidone,CYP3A4,CYP inhibition,Unknown,No,0,No
Loperamide,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Bicalutamide,Lansoprazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Rofecoxib,Bortezomib,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Vincristine,Isosorbide Mononitrate,CYP3A4,CYP inhibition,Unknown,No,0,No
Rofecoxib,Imatinib,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Ifosfamide,Metronidazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Enalapril,Sorafenib,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,No
Loperamide,Erlotinib,"ABCB1 (P-gp), CYP2C8","CYP inhibition, transporter inhibition",Unknown,No,0,No
Glibenclamide,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Bupropion,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Doxazosin,Imatinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Rofecoxib,Vincristine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Mitoxantrone,Temazepam,CYP3A4,CYP inhibition,Unknown,No,0,No
Pantoprazole,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Clomipramine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Alprazolam,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Metronidazole,Thiotepa,CYP3A4,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Promethazine,CYP2D6,CYP inhibition,Unknown,No,0,No
Carvedilol,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Hydroxyzine,Imatinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Loratadine,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Erythromycin,5-Fluorouracil,"CYP1A2, SLC22A7","CYP inhibition, transporter inhibition",Unknown,No,0,No
Theophylline,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Rac-Efavirenz,5-Fluorouracil,CYP2C9,CYP inhibition,Unknown,No,0,Yes
Valdecoxib,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Carbamazepine,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Cimetidine,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Propranolol,Gefitinib,"ABCB1 (P-gp), CYP2C19","CYP inhibition, transporter inhibition",Unknown,No,0,No
Irbesartan,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Clomipramine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Lovastatin,Capecitabine,CYP2C9,"CYP induction, CYP inhibition",Unknown,No,0,No
Valproic Acid,Dasatinib,CYP1A2,CYP inhibition,Unknown,No,0,No
Verapamil,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fenofibrate,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Timolol,Bortezomib,CYP2C19,CYP inhibition,Unknown,No,0,No
Letrozole,Metronidazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Nortriptyline,Gefitinib,CYP2C9,CYP inhibition,Unknown,No,0,No
Busulfan,Lansoprazole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
5-Fluorouracil,Glimepiride,CYP2C9,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Methylphenidate,CYP2D6,CYP inhibition,Unknown,No,0,No
Valproic Acid,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Arthrotec,Capecitabine,CYP2C9,CYP inhibition,Unknown,No,0,No
Raloxifene,Gefitinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Lovastatin,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Valproic Acid,5-Fluorouracil,"CYP2A6, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Cyclophosphamide,Ritonavir,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,Yes
Acetaminophen,Flutamide,"CYP1A2, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Ketotifen,Methotrexate,PGD,CYP inhibition,Unknown,No,0,No
Clopidogrel,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Methylphenidate,Imatinib,CYP2D6,CYP inhibition,Unknown,No,0,No
Indomethacin,Gefitinib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Pyrazinamide,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Fluconazole,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Isradipine,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Bortezomib,Valdecoxib,CYP2C9,CYP inhibition,Unknown,No,0,No
Tramadol,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Metronidazole,Fulvestrant,CYP3A4,CYP inhibition,Unknown,No,0,No
Vincristine,Palonosetron,CYP3A4,CYP inhibition,Unknown,No,0,No
Pioglitazone,Gefitinib,"CYP2C9, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Chlorpheniramine,Cyclophosphamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Imatinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Diazepam,Erlotinib,CYP2C8,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Zopiclone,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Propranolol,Arsenic Trioxide,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter inhibition",Unknown,No,0,Yes
Acebutolol,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Anastrozole,Mirtazapine,CYP3A4,CYP inhibition,Unknown,No,0,No
Tamoxifen,Thiotepa,"CYP2B6, CYP3A4","CYP induction, CYP inhibition",Unknown,No,0,No
Mitoxantrone,Tramadol,CYP3A4,CYP inhibition,Unknown,No,0,No
Tamoxifen,CID 152945,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Vincristine,CID 152945,CYP3A4,CYP inhibition,Unknown,No,0,No
Mitoxantrone,CID 152945,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Methylphenidate,CYP2D6,CYP inhibition,Unknown,No,0,No
Donepezil,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Losartan,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Raloxifene,Dasatinib,CYP3A4,CYP inhibition,Unknown,No,0,No
Donepezil,Leflunomide,CYP2C9,CYP inhibition,Unknown,No,0,No
Hydroxyurea,Ropinirole,CYP2D6,CYP inhibition,Unknown,No,0,No
Imipramine,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Doxazosin,Tamoxifen,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Buspirone,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Buspirone,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Meperidine,Mitoxantrone,CYP3A4,CYP inhibition,Unknown,No,0,No
Arsenic Trioxide,Ezetimibe,"ABCC2 (MRP2), CYP3A4","CYP inhibition, transporter induction",Unknown,No,0,No
Buspirone,Mitoxantrone,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Celecoxib,Tolcapone,CYP2C9,CYP inhibition,Unknown,No,0,No
Tamoxifen,Timolol,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Methylphenidate,Sorafenib,CYP2D6,CYP inhibition,Unknown,No,0,No
Celecoxib,Arsenic Trioxide,CYP3A4,CYP inhibition,Unknown,No,0,No
Phenytoin,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,Yes
Mirtazapine,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Lovastatin,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Meperidine,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Nifedipine,Temozolomide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Acebutolol,Bicalutamide,CYP2D6,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Risperidone,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Phentermine,Sorafenib,"CYP1A2, CYP2C9","CYP induction, CYP inhibition",Unknown,No,0,No
Fentanyl,Vinblastine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Phenytoin,Anastrozole,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Lidocaine,Vincristine,"ABCB1 (P-gp), CYP3A4","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Gefitinib,Methimazole,CYP3A4,CYP inhibition,Unknown,No,0,No
Temozolomide,Tramadol,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Oxybutynin,Sorafenib,CYP3A4,CYP inhibition,Unknown,No,0,No
Cyclophosphamide,Felodipine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Nisoldipine,Tamoxifen,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Indomethacin,Sorafenib,"ABCB1 (P-gp), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Mexiletine,Bortezomib,CYP1A2,CYP inhibition,Unknown,No,0,No
Doxazosin,Hydroxyurea,CYP2D6,CYP inhibition,Unknown,No,0,No
Carbamazepine,Ifosfamide,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Hydroxyurea,Itrizole,CYP2D6,CYP inhibition,Unknown,No,0,No
Isradipine,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Chloroquine,Cyclophosphamide,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
Chlorpheniramine,Vincristine,CYP3A4,CYP inhibition,Unknown,No,0,No
Ketoprofen,Sorafenib,"ABCC4 (MRP4), CYP2C9","CYP inhibition, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Nisoldipine,"ABCB1 (P-gp), CYP3A4","CYP induction, CYP inhibition, transporter inhibition",Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Gefitinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Metronidazole,Exemestane,CYP3A4,CYP inhibition,Unknown,No,0,No
Nifedipine,Arsenic Trioxide,"ABCB1 (P-gp), ABCC2 (MRP2), CYP3A4","CYP induction, CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Acebutolol,Gefitinib,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter inhibition",Unknown,No,0,No
Tamoxifen,Zopiclone,CYP3A4,"CYP induction, CYP inhibition",Unknown,No,0,No
Acebutolol,Tamoxifen,"ABCB1 (P-gp), CYP2D6","CYP inhibition, transporter induction, transporter inhibition",Unknown,No,0,No
Verapamil,Flutamide,CYP1A2,CYP inhibition,Unknown,No,0,No
Bupropion,Bicalutamide,CYP3A4,CYP inhibition,Unknown,No,0,No
Pantoprazole,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Ondansetron,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Citalopram,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Aspirin,Flutamide,CYP2C19,CYP induction,Unknown,No,0,No
Clonazepam,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Letrozole,Rofecoxib,CYP3A4,CYP induction,Unknown,No,0,No
Loperamide,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Prochlorperazine,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Prilosec,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Celecoxib,Oxcarbazepine,CYP3A4,CYP induction,Unknown,No,0,No
Bumetanide,Thalidomide,PTGS2,CYP induction,Unknown,No,0,No
Carvedilol,Carboplatin,XDH,CYP induction,Unknown,No,0,No
Carmustine,Pantoprazole,CYP1A2,CYP induction,Unknown,No,0,No
Cyclobenzaprine,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Oxybutynin,Thalidomide,CYP3A5,CYP induction,Unknown,No,0,No
Temozolomide,Zonisamide,CYP3A4,CYP induction,Unknown,No,0,No
Carbamazepine,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Carbamazepine,Celecoxib,CYP3A4,CYP induction,Unknown,No,0,No
Rofecoxib,Fulvestrant,CYP3A4,CYP induction,Unknown,No,0,No
Bupropion,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Carvedilol,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Temozolomide,Zolpidem,CYP3A4,CYP induction,Unknown,No,0,No
Aspirin,Cyclophosphamide,"ABCB1 (P-gp), CYP2C9","CYP induction, transporter inhibition",Unknown,No,0,No
Temazepam,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Pantoprazole,Exemestane,CYP3A4,CYP induction,Unknown,No,0,No
Phenytoin,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,Yes
Letrozole,Pantoprazole,CYP3A4,CYP induction,Unknown,No,0,No
Busulfan,Pantoprazole,CYP3A4,CYP induction,Unknown,No,0,No
Enalapril,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Pantoprazole,Fulvestrant,CYP3A4,CYP induction,Unknown,No,0,No
(3H)granisetron,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Fenofibrate,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Minoxidil,Bortezomib,PTGS1,CYP induction,Unknown,No,0,No
Letrozole,Pioglitazone,CYP3A4,CYP induction,Unknown,No,0,No
Celecoxib,Primidone,CYP3A4,CYP induction,Unknown,No,0,No
Salmeterol,Thalidomide,CYP3A5,CYP induction,Unknown,No,0,No
Indapamide,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Pioglitazone,Exemestane,CYP3A4,CYP induction,Unknown,No,0,No
Carbamazepine,Letrozole,CYP3A4,CYP induction,Unknown,No,0,No
Bumetanide,Lenalidomide,PTGS2,CYP induction,Unknown,No,0,No
Arthrotec,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Pioglitazone,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Temozolomide,Oxcarbazepine,CYP3A4,CYP induction,Unknown,No,0,No
Quetiapine,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Temozolomide,Tolterodine,CYP3A4,CYP induction,Unknown,No,0,No
Bisoprolol,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Carbamazepine,Fulvestrant,CYP3A4,CYP induction,Unknown,No,0,No
Temozolomide,Trimethoprim,CYP3A4,CYP induction,Unknown,No,0,No
Celecoxib,Pyridostigmine,CYP3A4,CYP induction,Unknown,No,0,No
Rofecoxib,Exemestane,CYP3A4,CYP induction,Unknown,No,0,No
Salmeterol,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
3-(1-Methylpyrrolidin-2-yl)pyridine,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Thalidomide,CID 152945,CYP3A5,CYP induction,Unknown,No,0,No
Donepezil,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Anzemet,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Carmustine,Lansoprazole,CYP1A2,CYP induction,Unknown,No,0,No
Oxazepam,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Rofecoxib,Temozolomide,CYP3A4,CYP induction,Unknown,No,0,No
Furosemide,6-Mercaptopurine,SLCO1B3? (OATP),transporter inhibition,Unknown,No,0,No
Methotrexate,Nifedipine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Ezetimibe,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Amitriptyline,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Metoprolol,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Lidocaine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Fluconazole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Verapamil,Methotrexate,"ABCB1 (P-gp), ABCC2 (MRP2)","transporter induction, transporter inhibition",Unknown,No,0,No
Terazosin,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Fentanyl,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Verapamil,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Lidocaine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Enalapril,5-Fluorouracil,SLC22A7,transporter inhibition,Unknown,No,0,No
Enalapril,Gefitinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Metoprolol,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Pantoprazole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Vincristine,Levetiracetam,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Felodipine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Bumetanide,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Unknown,No,0,No
Loratadine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Carbamazepine,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Glibenclamide,Carboplatin,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Metformin,Imatinib,SLC22A2,transporter inhibition,Unknown,No,0,No
Fexofenadine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Carvedilol,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Cimetidine,Methotrexate,"ABCB1 (P-gp), SLCO1B1 (OATP1B1)","transporter induction, transporter inhibition",Unknown,No,0,No
Ciprofloxacin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Lansoprazole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxepin,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Arsenic Trioxide,ABCC2 (MRP2),"transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Promethazine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Sumatriptan,"ABCB1 (P-gp), SLCO1A2 (OATP1A2)","transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Telmisartan,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Paroxetine,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Fexofenadine,Mitoxantrone,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Leflunomide,Telmisartan,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Venlafaxine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxepin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Glibenclamide,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Paroxetine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Fexofenadine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Clotrimazole,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Doxorubicin,Atazanavir,ABCC1,transporter inhibition,Unknown,No,0,Yes
Baclofen,Methotrexate,SLCO1B3? (OATP),transporter inhibition,Unknown,No,0,No
Imatinib,Terazosin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Acetazolamide,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Unknown,No,0,No
Promethazine,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Phosphonatoformate,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Unknown,No,0,Yes
Methotrexate,Atazanavir,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,Yes
Lidocaine,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Acetaminophen,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Dasatinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Dipyridamole,5-Fluorouracil,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Fentanyl,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),Cyclophosphamide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Indomethacin,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Rofecoxib,6-Mercaptopurine,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Vincristine,Zoledronic Acid,ABCC1,transporter inhibition,Unknown,No,0,No
Enalapril,Erlotinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Desloratadine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Ibuprofen,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Amlodipine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Clomipramine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
5-Fluorouracil,Telmisartan,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Cyclophosphamide,Doxazosin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Propranolol,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Furosemide,Tamoxifen,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Methotrexate,Venlafaxine,"ABCB1 (P-gp), ABCG2 (BCRP)","transporter induction, transporter inhibition",Unknown,No,0,No
8-iso Prostaglandin E1,Methotrexate,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Sumatriptan,Tamoxifen,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Mitoxantrone,Promethazine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Imipramine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Cyclophosphamide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Cyclophosphamide,Prazosin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Verapamil,Carboplatin,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Doxazosin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Scopolamine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Mitoxantrone,Paroxetine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
1-(2-Methyl-3-sulfanylpropanoyl)proline,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Dipyridamole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Dipyridamole,Gefitinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Lansoprazole,Clofarabine,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Enalapril,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Losartan,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxorubicin,Ibuprofen,ABCC1,transporter inhibition,Unknown,No,0,No
Metoprolol,Mitoxantrone,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Buspirone,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Losartan,Methotrexate,SLCO1B1 (OATP1B1),transporter inhibition,Unknown,No,0,No
Carvedilol,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxorubicin,Glibenclamide,ABCC1,transporter inhibition,Unknown,No,0,No
Methotrexate,Terazosin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Felodipine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Terazosin,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Azelastine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Lamotrigine,Imatinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Pantoprazole,Clofarabine,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Bumetanide,5-Fluorouracil,SLC22A7,transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),Valproic Acid,SLC22A5,transporter inhibition,Unknown,No,0,No
Buspirone,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Pantoprazole,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Cyclophosphamide,Dipyridamole,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Cyclophosphamide,Scopolamine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Loperamide,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Furosemide,Sorafenib,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Mitoxantrone,Zoledronic Acid,ABCC1,transporter inhibition,Unknown,No,0,No
Imatinib,Levetiracetam,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Metoprolol,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Terazosin,Sorafenib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Aspirin,Mitoxantrone,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Ibuprofen,Mitoxantrone,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Nisoldipine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Aspirin,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Amlodipine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Nadolol,Sorafenib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Paroxetine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Itrizole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Enalapril,Dasatinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Fluoxetine,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Promethazine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Valproic Acid,6-Mercaptopurine,SLCO1B3? (OATP),transporter inhibition,Unknown,No,0,No
Doxazosin,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Furosemide,Vincristine,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),Amlodipine,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Mitomycin C,Gefitinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxorubicin,Arthrotec,ABCC1,transporter inhibition,Unknown,No,0,No
Chlorambucil,Simvastatin,SLCO1A2 (OATP1A2),transporter inhibition,Unknown,No,0,No
Cyclophosphamide,Levetiracetam,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Loratadine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Levetiracetam,Gefitinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Carvedilol,Erlotinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Loperamide,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Vincristine,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Propafenone,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Metoprolol,Arsenic Trioxide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,Yes
Mitoxantrone,Sumatriptan,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Ketoconazole,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Fluoxetine,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Vinblastine,Zoledronic Acid,ABCC1,"transporter induction, transporter inhibition",Unknown,No,0,No
Methotrexate,Nitrazepam,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Acetaminophen,Dactinomycin (USP),ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Indomethacin,Carboplatin,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Metformin,Vincristine,SLC22A3,transporter inhibition,Unknown,No,0,No
Nizatidine,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Ibuprofen,6-Mercaptopurine,SLCO1B3? (OATP),transporter inhibition,Unknown,No,0,No
Dipyridamole,Methotrexate,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Loperamide,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Methotrexate,Miconazole,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Glibenclamide,Methotrexate,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Propranolol,Lenalidomide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxazosin,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Metoprolol,Dasatinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),Carbamazepine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Dactinomycin (USP),Methotrexate,ABCC1,transporter inhibition,Unknown,No,0,No
Lamotrigine,Tamoxifen,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Telmisartan,Erlotinib,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Carboplatin,Telmisartan,ABCC2 (MRP2),transporter inhibition,Unknown,No,0,No
Nifedipine,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Ritonavir,Carboplatin,"ABCC2 (MRP2), ABCG2 (BCRP)","transporter induction, transporter inhibition",Unknown,No,0,Yes
Dipyridamole,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Dipyridamole,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Celecoxib,6-Mercaptopurine,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Felodipine,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Arthrotec,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Levetiracetam,Sorafenib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Carvedilol,Dasatinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Mitoxantrone,Levetiracetam,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Paroxetine,Arsenic Trioxide,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Cyclophosphamide,Terazosin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Fexofenadine,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Verapamil,6-Mercaptopurine,ABCC4 (MRP4),transporter inhibition,Unknown,No,0,No
Dactinomycin (USP),1-(2-Methyl-3-sulfanylpropanoyl)proline,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Doxazosin,Erlotinib,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Mitomycin C,Simvastatin,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Diazepam,Mitomycin C,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Carboplatin,Dasatinib,ABCG2 (BCRP),transporter inhibition,Unknown,No,0,No
Lamotrigine,Vincristine,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Vincristine,Telmisartan,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Trimethoprim,Lenalidomide,ABCB1 (P-gp),"transporter induction, transporter inhibition",Unknown,No,0,No
Methadone,Methotrexate,ABCB1 (P-gp),transporter inhibition,Unknown,No,0,No
Venlafaxine,Carboplatin,ABCG2 (BCRP),transporter induction,Unknown,No,0,No
Methotrexate,Trazodone,ABCB1 (P-gp),transporter induction,Unknown,No,0,No
Clotrimazole,Carboplatin,ABCC2 (MRP2),transporter induction,Unknown,No,0,No
Nifedipine,Carboplatin,ABCC2 (MRP2),transporter induction,Unknown,No,0,No