diff --git a/.github/workflows/python-package-conda.yml b/.github/workflows/python-package-conda.yml
index f767a06e..5c148f55 100644
--- a/.github/workflows/python-package-conda.yml
+++ b/.github/workflows/python-package-conda.yml
@@ -9,8 +9,8 @@ on:
     branches: [ master ]
 
 env:
-  latest_python: "3.14"
-  supported_pythons: '["3.9", "3.10", "3.11", "3.12", "3.13", "3.14"]'
+  latest_python: "3.15"
+  supported_pythons: '["3.9", "3.10", "3.11", "3.12", "3.13", "3.14", "3.15"]'
   miniforge_version: "23.11.0-0"
   miniforge_variant: "Mambaforge"
 
@@ -34,7 +34,7 @@ jobs:
     needs: conf
     runs-on: "ubuntu-latest"
     steps:
-      - uses: actions/checkout@v4
+      - uses: actions/checkout@v7
       - uses: conda-incubator/setup-miniconda@v3
         with:
           auto-update-conda: true
@@ -56,7 +56,7 @@ jobs:
     needs: ["conf", "lint"]
     runs-on: "ubuntu-latest"
     steps:
-      - uses: actions/checkout@v4
+      - uses: actions/checkout@v7
       - uses: conda-incubator/setup-miniconda@v3
         with:
           auto-update-conda: true
@@ -81,11 +81,11 @@ jobs:
     strategy:
       fail-fast: true
       matrix:
-        os: [ubuntu-latest, macos-latest, windows-latest, ubuntu-24.04-arm, macos-15-intel]
+        os: [ubuntu-latest, macos-latest, windows-latest, ubuntu-24.04-arm, macos-26-intel]
         python_version: ${{ fromJSON(needs.conf.outputs.supported_pythons) }}
         use_conda: [true, false]
     steps:
-      - uses: actions/checkout@v4
+      - uses: actions/checkout@v7
       - uses: conda-incubator/setup-miniconda@v3
         with:
           auto-update-conda: true
diff --git a/.github/workflows/wheels.yml b/.github/workflows/wheels.yml
index e29e7339..c479a6a7 100644
--- a/.github/workflows/wheels.yml
+++ b/.github/workflows/wheels.yml
@@ -18,7 +18,7 @@ jobs:
     runs-on: ${{ matrix.os }}
     strategy:
       matrix:
-        os: [ubuntu-latest, ubuntu-24.04-arm, windows-latest, macos-15, macos-15-intel]
+        os: [ubuntu-latest, ubuntu-24.04-arm, windows-latest, macos-latest, macos-26-intel]
         # The 5 runners correspond to 5 architectures. Details:
         # https://cibuildwheel.pypa.io/en/stable/options/#archs
         # The runners and architectures should be automatically associated. However, in
@@ -30,20 +30,20 @@ jobs:
         #     cibw_archs: 'aarch64'
         #   - os: windows-latest
         #     cibw_archs: 'AMD64'
-        #   - os: macos-13
-        #     cibw_archs: 'x86_64'
         #   - os: macos-latest
         #     cibw_archs: 'arm64'
+        #   - os: macos-26-intel
+        #     cibw_archs: 'x86_64'
 
     steps:
-      - uses: actions/checkout@v4
+      - uses: actions/checkout@v7
         with:
           submodules: true
 
       - name: Build wheels
-        uses: pypa/cibuildwheel@v3.4.1
+        uses: pypa/cibuildwheel@v4.3.0
 
-      - uses: actions/upload-artifact@v4
+      - uses: actions/upload-artifact@v7
         with:
           name: wheels-${{ matrix.os }}-${{ strategy.job-index }}
           path: ./wheelhouse/*.whl
@@ -52,12 +52,12 @@ jobs:
     name: Build source distribution
     runs-on: ubuntu-latest
     steps:
-      - uses: actions/checkout@v4
+      - uses: actions/checkout@v7
         with:
           submodules: true
 
       - name: Set up Python
-        uses: actions/setup-python@v5
+        uses: actions/setup-python@v7
         with:
           python-version: '3.9'
 
@@ -68,7 +68,7 @@ jobs:
       - name: Build sdist
         run: python -m build --sdist
 
-      - uses: actions/upload-artifact@v4
+      - uses: actions/upload-artifact@v7
         with:
           name: sdist
           path: dist/*.tar.gz
@@ -79,13 +79,13 @@ jobs:
     # Only upload to PyPI on tagged commits
     if: github.event_name == 'push' && startsWith(github.ref, 'refs/tags')
     steps:
-      - uses: actions/download-artifact@v4
+      - uses: actions/download-artifact@v8
         with:
           pattern: wheels-*
           path: dist
           merge-multiple: true
 
-      - uses: actions/download-artifact@v4
+      - uses: actions/download-artifact@v8
         with:
           name: sdist
           path: dist
diff --git a/ChangeLog.md b/ChangeLog.md
index cfa6197b..062eb015 100644
--- a/ChangeLog.md
+++ b/ChangeLog.md
@@ -1,6 +1,14 @@
 BIOM-Format ChangeLog
 =====================
 
+biom-2.1.19-dev
+---------------
+
+General Maintenance:
+
+* Python 3.15 added to CI and wheels are now built for Python 3.15. See PR [#1008](https://github.com/biocore/biom-format/pull/1008)
+
+
 biom-2.1.18
 -----------
 
diff --git a/pyproject.toml b/pyproject.toml
index 67532d04..069713e7 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -40,6 +40,7 @@ classifiers = [
     "Programming Language :: Python :: 3.12",
     "Programming Language :: Python :: 3.13",
     "Programming Language :: Python :: 3.14",
+    "Programming Language :: Python :: 3.15",
     "Programming Language :: Python :: Implementation :: CPython",
     "Operating System :: OS Independent",
     "Operating System :: POSIX :: Linux",
@@ -84,7 +85,7 @@ test-requires = ["pytest", "numpy"]
 skip = ["*-win32", "*-manylinux_i686", "pp*", "*-musllinux*"]
 
 # Python versions to build
-build = "cp39-* cp310-* cp311-* cp312-* cp313-* cp314-*"
+build = "cp39-* cp310-* cp311-* cp312-* cp313-* cp314-* cp315-*"
 
 [tool.pytest.ini_options]
 addopts = ["--ignore=biom/assets/exercise_api.py "]