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4 | 4 | <title>Computo Journal - Recent Articles</title> |
5 | 5 | <link>https://computo-journal.org/</link> |
6 | 6 | <description>Latest published articles from Computo Journal</description> |
| 7 | + <item> |
| 8 | + <title>Comparative analysis of stopping criteria for multi-objective evolutionary algorithms: from benchmark problems to industrial application - Manon Perrignon, Magalie Houée-Bigot, Romain Jeantet, Thomas Croguennec and Mathieu Emily</title> |
| 9 | + <link>https://computo-journal.org/published-202609-perrignon-multi/</link> |
| 10 | + <guid>https://computo-journal.org/published-202609-perrignon-multi/</guid> |
| 11 | + <pubDate>Thu, 03 Sep 2026 00:00:00 GMT</pubDate> |
| 12 | + <description>Multi-objective optimization problems are commonly solved |
| 13 | + using evolutionary algorithms, which typically terminate after a |
| 14 | + user-defined number of generations without guaranteeing solution |
| 15 | + optimality. Stopping criteria can address this limitation by |
| 16 | + determining when the algorithm has converged to high-quality |
| 17 | + solutions. This study compares four existing stopping criteria and |
| 18 | + proposes a novel criterion designed to balance computational cost |
| 19 | + and solution quality. The criteria are first evaluated on classical |
| 20 | + multi-objective benchmark problems, then applied to test cases where |
| 21 | + optimal solutions are known and can be compared with those obtained |
| 22 | + after implementing each stopping criterion. Finally, the criteria |
| 23 | + are applied to a food process optimization case study. This analysis |
| 24 | + identifies the most effective criterion for achieving this trade-off |
| 25 | + in practical applications.</description> |
| 26 | + </item> |
7 | 27 | <item> |
8 | 28 | <title>Should we correct the bias in Confidence Bands for Repeated Functional Data? - Emilie Devijver and Adeline Samson</title> |
9 | 29 | <link>https://computo-journal.org/published-202606-devijver-scb/</link> |
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27 | 47 | extensive simulation study. We conclude with an application to real |
28 | 48 | data.</description> |
29 | 49 | </item> |
| 50 | + <item> |
| 51 | + <title>Detecting adverse high-order drug combinations from individual case safety reports using computational statistics on disproportionality measures - Jules Bangard, Einar Holsbø, Kristian Svendsen, Vittorio Perduca and Étienne Birmelé</title> |
| 52 | + <link>https://computo-journal.org/published-202605-bangard-adverse/</link> |
| 53 | + <guid>https://computo-journal.org/published-202605-bangard-adverse/</guid> |
| 54 | + <pubDate>Wed, 15 Jul 2026 00:00:00 GMT</pubDate> |
| 55 | + <description>Adverse drug reactions linked to the intake of drug |
| 56 | + combinations are a critical concern in pharmacovigilance, |
| 57 | + particularly as the controlled environment of clinical trials often |
| 58 | + lacks the scale and diversity to detect rare events involving |
| 59 | + multiple medications. While spontaneous reporting systems provide |
| 60 | + the necessary breadth for post-market surveillance, identifying |
| 61 | + overrepresented drug cocktails within such large-scale data remains |
| 62 | + a significant computational challenge. This study introduces a |
| 63 | + computational framework for the detection of drug cocktails |
| 64 | + associated with adverse events, leveraging disproportionality |
| 65 | + analysis on individual case safety reports. By integrating the |
| 66 | + Anatomical Therapeutic Chemical classification, the framework |
| 67 | + extends beyond individual drugs to capture hierarchical |
| 68 | + pharmacological relationships, enabling exploration of the space of |
| 69 | + drug combinations beyond pairwise analysis. To address biases |
| 70 | + inherent in existing disproportionality measures, we employ a |
| 71 | + hypergeometric risk metric, while a Markov Chain Monte Carlo |
| 72 | + algorithm provides robust empirical p-value estimation for the risk |
| 73 | + associated with cocktails. A genetic algorithm further facilitates |
| 74 | + efficient identification of high-risk drug cocktails. A |
| 75 | + post-treatment step based on penalized logistic regression allows |
| 76 | + distinguishing true pharmacological interactions from combined |
| 77 | + individual effects for cocktails of any size. Validation on |
| 78 | + synthetic and FDA Adverse Event Reporting System data demonstrates |
| 79 | + the method’s efficacy in detecting established drugs and drug |
| 80 | + combinations associated with myopathy-related adverse events. |
| 81 | + Implemented as an R package, this framework offers a reproducible, |
| 82 | + scalable tool for post-market drug safety surveillance.</description> |
| 83 | + </item> |
30 | 84 | <item> |
31 | 85 | <title>Variational inference for approximate objective priors using neural networks - Nils Baillie, Antoine Van Biesbroeck and Clément Gauchy</title> |
32 | 86 | <link>https://computo-journal.org/published-202512-baillie-varp/</link> |
|
173 | 227 | efficient algorithms based on thinning methods, which are compiled |
174 | 228 | using the `Rcpp` package while providing a user-friendly interface.</description> |
175 | 229 | </item> |
176 | | - <item> |
177 | | - <title>Spectral Bridges - Félix Laplante and Christophe Ambroise</title> |
178 | | - <link>http://computo-journal.org/published-202412-ambroise-spectral/</link> |
179 | | - <guid>http://computo-journal.org/published-202412-ambroise-spectral/</guid> |
180 | | - <pubDate>Fri, 13 Dec 2024 00:00:00 GMT</pubDate> |
181 | | - <description>In this paper, Spectral Bridges, a novel clustering |
182 | | - algorithm, is introduced. This algorithm builds upon the traditional |
183 | | - k-means and spectral clustering frameworks by subdividing data into |
184 | | - small Voronoï regions, which are subsequently merged according to a |
185 | | - connectivity measure. Drawing inspiration from Support Vector |
186 | | - Machine’s margin concept, a non-parametric clustering approach is |
187 | | - proposed, building an affinity margin between each pair of Voronoï |
188 | | - regions. This approach delineates intricate, non-convex cluster |
189 | | - structures and is robust to hyperparameter choice. The numerical |
190 | | - experiments underscore Spectral Bridges as a fast, robust, and |
191 | | - versatile tool for clustering tasks spanning diverse domains. Its |
192 | | - efficacy extends to large-scale scenarios encompassing both |
193 | | - real-world and synthetic datasets. The Spectral Bridge algorithm is |
194 | | - implemented both in Python (\textless |
195 | | - https://pypi.org/project/spectral-bridges\textgreater) and R |
196 | | - \textless |
197 | | - https://github.com/cambroise/spectral-bridges-Rpackage\textgreater).</description> |
198 | | - </item> |
199 | | - <item> |
200 | | - <title>AdaptiveConformal: An `R` Package for Adaptive Conformal Inference - Herbert Susmann, Antoine Chambaz and Julie Josse</title> |
201 | | - <link>http://computo-journal.org/published-202407-susmann-adaptive-conformal/</link> |
202 | | - <guid>http://computo-journal.org/published-202407-susmann-adaptive-conformal/</guid> |
203 | | - <pubDate>Thu, 18 Jul 2024 00:00:00 GMT</pubDate> |
204 | | - <description>Conformal Inference (CI) is a popular approach for |
205 | | - generating finite sample prediction intervals based on the output of |
206 | | - any point prediction method when data are exchangeable. Adaptive |
207 | | - Conformal Inference (ACI) algorithms extend CI to the case of |
208 | | - sequentially observed data, such as time series, and exhibit strong |
209 | | - theoretical guarantees without having to assume exchangeability of |
210 | | - the observed data. The common thread that unites algorithms in the |
211 | | - ACI family is that they adaptively adjust the width of the generated |
212 | | - prediction intervals in response to the observed data. We provide a |
213 | | - detailed description of five ACI algorithms and their theoretical |
214 | | - guarantees, and test their performance in simulation studies. We |
215 | | - then present a case study of producing prediction intervals for |
216 | | - influenza incidence in the United States based on black-box point |
217 | | - forecasts. Implementations of all the algorithms are released as an |
218 | | - open-source `R` package, `AdaptiveConformal`, which also includes |
219 | | - tools for visualizing and summarizing conformal prediction |
220 | | - intervals.</description> |
221 | | - </item> |
222 | 230 | </channel> |
223 | 231 | </rss> |
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