A toolkit developed to predict and analyze PROTAC-mediated ternary complexes using AlphaFold3 and Boltz-1.
PROTAC-Splitter: a machine learning framework designed for automated annotation of PROTAC substructures.
Predicting PROTAC protein degradation activity via machine learning.
Empirical evaluation of which public-data features actually predict PROTAC E3-ligase tractability — and which merely track how well-studied a ligase is.
Kymera Therapeutics — independent third-party profile of a public API surface, by API Evangelist. Kymera Therapeutics is a clinical-stage biopharmaceutical company headquartered at 500 North Beacon Street in Watertown, Massachusetts, pioneering targeted protein degradation as a way to build oral small-molecule medicines against targets that convent
PROTACXtend — open-source agentic AI platform for PROTAC discovery & design: generative linker assembly, ternary complex simulation, degradation (DC50/Dmax) & ADMET prediction. By Saveena Solanki & Ahuja Lab, IIIT Delhi.
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